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Documentos clave

217503

Sigma-Aldrich

Cardiotoxin

from Naja pallida, ≥95% (HPLC), lyophilized solid, cytolytic toxin, Calbiochem®

Sinónimos:

Cardiotoxin, Naja pallida

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About This Item

Número de CAS:
11061-96-4
MDL number:
MFCD00149694
UNSPSC Code:
12352202
NACRES:
NA.32
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Nombre del producto

Cardiotoxin, Naja pallida,

assay

≥95% (HPLC)

Quality Level

100

form

lyophilized solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

solubility

water: 1 mg/mL

shipped in

ambient

storage temp.

2-8°C

General description

Cardiotoxins, which are highly basic peptides, interact with negatively charged lipids on membranes. While the presence of Lysine residues is crucial for their activity, cardiotoxins demonstrate varying effects on different cells, indicating selective binding to certain cell types.[1]

Application

Cardiotoxin, Naja pallida has been used:
  • to inject into the TA of the 4-month-old dystrophic mice to address whether ILA treatment could modulate muscle regeneration[2]
  • to induce a skeletal muscle injury into the right TA muscle[3]
  • to induce muscle regeneration[4]

Warning

Toxicity: Harmful (C)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Jang, J.Y., et al. 1997. Biochemistry 36, 4635.
Huang, J.L., and Trumble, W.R. 1991. Toxicon29, 31.
Raynor, R.L., et al. 1991. J. Biol. Chem.266, 2753.
Grognet, J.M., et al. 1986. Mol. Immunol.23, 132.

Legal Information

Not available for sale outside of the United States.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Questions

  1. Re 217503 Cardiotoxin, Naja pallida - could you please ask your supplier for more details on this protein: which form of 3FTx is it ? Can they give me an accession number or a UniProt entry, thanks.

    1 answer

    1. This product is classified as Cytotoxin 1. The UniProt accession number is P01468. Please see the link below to review the UniProt profile:
      https://www.uniprot.org/uniprotkb/P01468/entry

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