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U5625

Sigma-Aldrich

Uridine 5′-diphosphoglucuronic acid ammonium salt

98-100%

Sinonimo/i:

UDP-GlcA, UDPGA, Uridine-diphosphate-glucuronic acid ammonium salt, Uridine[5′]diphospho[1]-α-D-glucopyranosuronic acid ammonium salt

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100 MG
CHF 395.00
250 MG
CHF 773.00
500 MG
CHF 1’360.00
1 G
CHF 2’150.00

CHF 395.00

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Tutte le immagini(5)

Scegli un formato

Cambia visualizzazione
100 MG
CHF 395.00
250 MG
CHF 773.00
500 MG
CHF 1’360.00
1 G
CHF 2’150.00

About This Item

Formula empirica (notazione di Hill):
C15H22N2O18P2 · xNH3
Numero CAS:
43195-60-4
Peso molecolare:
580.29 (free acid basis)
Codice UNSPSC:
41106305
ID PubChem:
24900657
NACRES:
NA.51

CHF 395.00

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Origine biologica

Saccharomyces cerevisiae
enzyme from bovine liver (catalase)
enzyme from rabbit muscle (LDH)

Saggio

98-100%

Stato

powder

Temperatura di conservazione

−20°C

Stringa SMILE

N.O[C@@H]1[C@@H](O)[C@H](O[C@@H]([C@H]1O)C(O)=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N3C=CC(=O)NC3=O

InChI

1S/C15H22N2O18P2.H3N/c18-5-1-2-17(15(26)16-5)12-9(22)6(19)4(32-12)3-31-36(27,28)35-37(29,30)34-14-10(23)7(20)8(21)11(33-14)13(24)25;/h1-2,4,6-12,14,19-23H,3H2,(H,24,25)(H,27,28)(H,29,30)(H,16,18,26);1H3/t4-,6-,7+,8+,9-,10-,11+,12-,14-;/m1./s1
WMWKTCPGFOEPBD-YGIWDPDDSA-N

Categorie correlate

Descrizione generale

Uridine 5′-diphosphoglucuronic acid (UDPGA) is a cofactor, synthesized from UDPglucose and nicotinamide adenine dinucleotide (NAD+) intracellularly by the catalytic activity of UDPglucose dehydrogenase. The concentration of UDPGA in a number of liver preparations ranges from 0.3-0.5 mM.[1]

Applicazioni

Uridine 5′-diphosphoglucuronic acid ammonium salt has been used in the initiation of UDP-glucuronosyl transferase (UDGPT) assay towards 14C-testosterone in the liver S9 protein.[2] It is suitable for use in UDGPT assay.[3][4]

Azioni biochim/fisiol

Uridine 5′-diphosphoglucuronic acid (UDGPA) is the glucuronic acid donor for the conjugation of bilirubin in the endoplasmic recticulum.[5]

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
0000427869
0000427868
0000427869
0000427868
0000371596

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Shupeng Yang et al.
Journal of agricultural and food chemistry, 65(51), 11292-11303 (2017-12-06)
To explore differences of zearalenone (ZEN) metabolism between various species, phase I and II metabolism by liver microsomes of animals and human were investigated using ultra high-pressure liquid chromatography-quadrupole/time-of-flight mass spectrometry (UHPLC-Q/TOF MS). A total of 24 metabolites were identified
Developmental exposure to low-dose PBDE-99: tissue distribution and thyroid hormone levels
Kuriyama SN, et al.
Toxicology, 242(1-3), 80-90 (2007)
Ankit Parikh et al.
International journal of pharmaceutics, 515(1-2), 490-500 (2016-11-05)
Edaravone (EDR), a strong free radical scavenger, is known for its promising therapeutic potential in oxidative stress (OS) associated diseases, however poor oral bioavailability is the major obstacle in its potential use. Oral liquid dosage form is the most preferred
Malgorzata Szultka-Mlynska et al.
Analytical and bioanalytical chemistry, 408(29), 8273-8287 (2016-10-25)
High performance liquid chromatography coupled with triple-quadrupole mass spectrometry was applied in the determination of in vitro metabolism products of selected antibiotic drugs (cefotaxime, ciprofloxacin, fluconazole, gentamicin, clindamycin, linezolid, and metronidazole). The analytes were separated on a reversed phase C18
The Isolated hepatocyte: Use in Toxicology and Xenobiotic Biotransformations, 26-26 (2012)
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