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Key Documents

95209

Sigma-Aldrich

Acido L-ascorbico

BioUltra, ≥99.5% (RT)

Sinonimo/i:

Acido L-treoascorbico, Fattore antiscorbuto, Vitamina C

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About This Item

Formula empirica (notazione di Hill):
C6H8O6
Numero CAS:
Peso molecolare:
176.12
Beilstein:
84272
Numero CE:
Numero MDL:
Codice UNSPSC:
12352205
ID PubChem:
NACRES:
NA.79

Origine biologica

synthetic

Livello qualitativo

Nome Commerciale

BioUltra

Saggio

≥99.5% (RT)

Forma fisica

powder or crystals

Impurezze

insoluble matter, passes filter test

Residuo alla calcinazione

≤0.05% (as SO4)

Perdita

≤0.05% loss on drying, 20 °C (HV)

Colore

white to off-white

pH

1.0-2.5 (25 °C, 1 M in H2O)

Punto di fusione

190-194 °C (dec.)

Solubilità

H2O: 1 M at 20 °C, clear, colorless

Anioni in tracce

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤20 mg/kg

Cationi in tracce

Al: ≤5 mg/kg
As: ≤0.1 mg/kg
Ba: ≤5 mg/kg
Bi: ≤5 mg/kg
Ca: ≤25 mg/kg
Cd: ≤5 mg/kg
Co: ≤5 mg/kg
Cr: ≤5 mg/kg
Cu: ≤5 mg/kg
Fe: ≤5 mg/kg
K: ≤50 mg/kg
Li: ≤5 mg/kg
Mg: ≤5 mg/kg
Mn: ≤5 mg/kg
Mo: ≤5 mg/kg
Na: ≤50 mg/kg
Ni: ≤5 mg/kg
Pb: ≤5 mg/kg
Sr: ≤5 mg/kg
Zn: ≤5 mg/kg

Assorbimento

cut-off at 306 nm in H2O at 1 M

Stringa SMILE

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Informazioni sul gene

human ... SLC23A2(9962)

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Descrizione generale

L-Ascorbic acid, also known as vitamin C, is a water-soluble vitamin. It is naturally present in a variety of foods such as citrus fruits and vegetables. It is present only in minimal amount in milk.

Applicazioni

L-Ascorbic acid has been used as an antioxidant supplement in incubation solution for dissected and sliced brain sections. It has also been used as a supplement in phosphate-buffered saline (PBS) wash buffer during oxidative GFP chromophore formation.

Azioni biochim/fisiol

L-Ascorbic acid (Vitamin C) acts as a potential anti-oxidant and reducing agent. It prevents bacterial mutagenesis induced by N-nitroso compounds. In plants, vitamin C elicits several cellular processes such as growth, apoptosis, pathogen responses, hormone responses, flowering and senescence, and protection against environmental stresses. Vitamin C deficiency is associated with the development of scurvy, prominent - gingivitis, perifollicular hemorrhages, poor wound healing, petechiae and ecchymosis.

Altre note

Denaturation of proteins; Dimeric association of E. coli RNA polymerase α subunits, studied by cleavage of single cysteine α subunits conjugated to Fe-BABE.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 1

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


Certificati d'analisi (COA)

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F C Brown et al.
Neurochemical research, 3(3), 357-366 (1978-06-01)
Under conditions that are optimum for DbetaH, ascorbic acid denatures serum albumin, gamma-globulin, catalase, and DbetaH. With ascrobate plus Cu2+, the proteins are almost completely destroyed. Pyrazole protects DbetaH and albumin, but not catalase. Superoxide dismutase (SOD) is not denatured
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Inhibition by L-ascorbate of bacterial mutagenesis induced by two N-nitroso compounds
Guttenplan JB
Nature, 268(5618), 368-368 (1977)

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