47036

Saponina

Molecular Biology, used as non-ionic surfactant

• Sinonimo/i: Glycosides, Saponins
• Numero CAS: 8047-15-2
• UNSPSC Code: 12161900
• NACRES: NA.25
• EC Number: 232-462-6
• MDL number: MFCD00081981

Proprietà

• grade: Molecular Biology
• Quality Segment: 200
• mol wt: 1000-2000 g/mol
• composition: Sapogenin, 8-25%
• technique(s): HPLC: suitable, protein quantification: suitable
• CMC: 0.001-0.01%
• density: 1.015-1.020 g/mL at 20 °C (5% in H₂O)(lit.)
• foreign activity: DNase, RNase, Protease, Phosphatase, none detected
• SMILES string: C[C@]1(CCC23COC4([C@H]2C1)CC[C@@H]5[C@]6(CC[C@@H](C(C6CC[C@]5([C@@]4(C[C@H]3O)C)C)(C)C)O[C@H]7[C@@H]([C@H]([C@H](CO7)O[C@H]8[C@@H]([C@H]([C@@H](CO8)O)O)O)O[C@@H]9[C@@H]([C@H]([C@@H]([C@H](O9)CO)O)O)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)C)C=O
• InChI: 1S/C58H94O27/c1-52(2)29-7-11-55(5)30(8-12-58-31-15-53(3,22-62)13-14-57(31,23-77-58)32(64)16-56(55,58)6)54(29,4)10-9-33(52)82-50-46(85-51-45(40(71)37(68)27(19-61)80-51)84-49-43(74)39(70)36(67)26(18-60)79-49)44(83-48-42(73)38(69)35(66)25(17-59)78-48)28(21-76-50)81-47-41(72)34(65)24(63)20-75-47/h22,24-51,59-61,63-74H,7-21,23H2,1-6H3/t24-,25-,26-,27-,28+,29?,30-,31+,32-,33+,34+,35-,36-,37-,38+,39+,40+,41-,42-,43-,44+,45-,46-,47+,48-,49-,50+,51+,53-,54+,55-,56+,57?,58?/m1/s1
• InChI key: MAEBCGDGGATMSC-OSHGGGOQSA-N

Descrizione

General description

Saponins are a large family of amphiphilic glycosides of steroids and triterpenes. Saponins are found in many plants and are localized especially in the root, tuber, bark, leaves, seed, and fruit. They are also present in some animals, like sea cucumber.

Application

Glicoside usato come tensioattivo anionico coadiuvante di sviluppo del vaccino.

Saponin has been used:

• in phosphate-buffered saline (PBS) to block cells for immunocytochemistry and confocal microscopy
• to permeabilize cells for measuring total mitochondrial mass
• as an internal control to extract saponin Holothuria nobilis Selenka

Biochem/physiol Actions

Le saponine sono tensioattivi non-ionici che formano emulsioni olio-in-acqua e agiscono come colloidi protettivi. Sono usate per la determinazione diretta dei metalli nel latte mediante spettrofotometria di assorbimento atomico con atomizzazione in fiamma.

Saponins exhibit anti-tumor, antimicrobial, and anti-herbivore activity. They may also play a key role in plant defense. Saponins also possess several pharmaceutical properties, like anti-inflammatory, antifungal, antibacterial, anti-parasitic, and antiviral activities. Saponins can regulate rhizosphere bacteria in the soil.

Informazioni sulla sicurezza

• pictograms: GHS07
• signalword: Warning
• hcodes: H319,H335
• pcodes: P261 - P264 - P271 - P280 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Classe di stoccaggio: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves