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Merck

P5710

Sigma-Aldrich

D-Pantothensäure Hemicalciumsalz

BioXtra

Synonym(e):

(R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanin Hemicalciumsalz, D-Pantothensäure Calciumsalz, Calcium-D-pantothenat, Vitamin B5

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About This Item

Lineare Formel:
HOCH2C(CH3)2CH(OH)CONHCH2CH2CO2 ·1/2Ca
CAS-Nummer:
Molekulargewicht:
238.27
Beilstein:
3769272
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352200
PubChem Substanz-ID:

Produktlinie

BioXtra

Form

powder

Verunreinigungen

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

Farbe

white to off-white

Löslichkeit

H2O: 0.5 M, clear, colorless

Anionenspuren

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

Kationenspuren

Al: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.01%
NH4+: ≤0.05%
Na: ≤0.005%
Pb: ≤0.001%
Zn: ≤0.0005%

Lagertemp.

2-8°C

SMILES String

CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)[C@H](O)C(C)(C)CO

InChI

1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1

InChIKey

FAPWYRCQGJNNSJ-UBKPKTQASA-L

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Anwendung

Vorläufer für die Biosynthese von Coenzym A

Biochem./physiol. Wirkung

D-Panthenol is the alcohol analogue and biological precursor of D-pantothenic acid. These analogues are precursors in the biosynthesis of coenzyme A. D-Panthenol and D-Pantothenic acid are used in a variety of skin protection products. D-pantothenic acid may have a role in controlling keratinocyte proliferation and differentiation. D-Panthenol may be used for studies of skin protection emulsions from UV irradiation and as a humectant.

Physikalische Eigenschaften

Aufgrund der instabilen, hygroskopischen Natur der freien Säure, wird das Calciumsalz verwendet.

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Michael Habig et al.
Journal of biomolecular screening, 14(6), 679-689 (2009-05-28)
High-throughput screening often identifies not only specific, stoichiometrically binding inhibitors but also undesired compounds that unspecifically interfere with the targeted activity by nonstoichiometrically binding, unfolding, and/or inactivating proteins. In this study, the effect of such unwanted inhibitors on several different
C F Zanatta et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 48(1), 70-75 (2009-09-22)
Considering the belief that natural lipids are safer for topical applications and that carotenoids are able to protect cells against photooxidative damage, we have investigated whether topical creams and lotions, produced with Buriti oil and commercial surfactants, can exert photoprotective
X Hui et al.
International journal of cosmetic science, 29(4), 277-282 (2008-05-21)
The in vitro absorption of panthenol into and through the human nail was examined in this study. Panthenol, the alcohol form of pantothenic acid (vitamin B5), is believed to act as a humectant and improve the flexibility and strength of
D Hoeller Obrigkeit et al.
Cutaneous and ocular toxicology, 25(1), 13-22 (2006-05-17)
To investigate the effect of cell growth-stimulating agents on human epidermal keratinocytes, we exposed monolayers of normal human keratinocytes derived from foreskin to different concentrations of the amino acid L-cystine, the member of the vitamin B family D-pantothenat, the phytosterol
Tonio Wiederholt et al.
Experimental dermatology, 18(11), 969-978 (2009-04-29)
Topical application of pantothenate is widely used in clinical practice for wound healing. Previous studies identified a positive effect of pantothenate on migration and proliferation of cultured fibroblasts. However, these studies were mainly descriptive with no molecular data supporting a

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