P5155

D-Pantothensäure Hemicalciumsalz

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

• Synonym(e): (R)-(+)-N-(2,4-Dihydroxy-3,3-dimethyl-1-oxobutyl)-β-alanin Hemicalciumsalz, D-Pantothensäure Calciumsalz, Calcium-D-pantothenat, Vitamin B₅
• Lineare Formel: HOCH₂C(CH₃)₂CH(OH)CONHCH₂CH₂CO₂ ·1/2Ca
• CAS-Nummer: 137-08-6
• Molekulargewicht: 238.27
• Beilstein: 3769272
• EG-Nummer: 205-278-9
• MDL-Nummer: MFCD00002766
• UNSPSC-Code: 12352205
• eCl@ss: 34058012
• PubChem Substanz-ID: 24898601
• NACRES: NA.75

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Produktlinie: BioReagent
• Assay: ≥98% (TLC)
• Form: powder
• Mol-Gew.: M_w 238.27 g/mol
• Methode(n): cell culture | insect: suitable; cell culture | mammalian: suitable; cell culture | plant: suitable
• Farbe: white to off-white
• pH-Wert: 7.0-8 (25 °C, 50 g/L)
• Löslichkeit: water: soluble 50 mg/mL, clear, colorless
• Lagertemp.: 2-8°C
• SMILES String: CC(C)(CO)[C@@H](O)C(=O)NCCC(=O)O[Ca]OC(=O)CCNC(=O)[C@H](O)C(C)(C)CO
• InChI: 1S/2C9H17NO5.Ca/c2*1-9(2,5-11)7(14)8(15)10-4-3-6(12)13;/h2*7,11,14H,3-5H2,1-2H3,(H,10,15)(H,12,13);/q;;+2/p-2/t2*7-;/m00./s1
• InChIKey: FAPWYRCQGJNNSJ-UBKPKTQASA-L

Beschreibung

Allgemeine Beschreibung

Plants and microorganisms, such as Escherichia coli are the major sources of D-pantothenic acid. It is water soluble and quite stable to heating.

Anwendung

D-Pantothenic acid hemicalcium salt has been used:

• as a component of FMX-turbodoma- derived media
• as a supplement in DMEM (Dulbecco′s modified eagle media)/F-12 used for cell proliferation
• as a supplement in preadipocyte media

Vorläufer für die Biosynthese von Coenzym A

Biochem./physiol. Wirkung

Along with coenzyme A (CoA, D-pantothenic acid is a precursor for acyl carrier protein. These are essential cofactors involved in fat, protein and carbohydrate metabolism. It also participates in the formation of acetylcholine neurotransmitter. D-pantothenic acid is considered as a source of nutrition and possesses immune function by mediating antibody formation. The production of cortisone is supported by D-pantothenic acid. It is essential for adrenal gland activity.

Physikalische Eigenschaften

Aufgrund der instabilen, hygroskopischen Natur der freien Säure, wird das Calciumsalz verwendet.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)