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O7753

Sigma-Aldrich

Oxalessigsäure

powder, BioReagent, suitable for cell culture, suitable for insect cell culture, ≥97% (HPLC)

Synonym(e):

2-Ketobernsteinsäure, 2-Oxobernsteinsäure, Oxobutandisäure

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5 G
CHF 250.00
25 G
CHF 427.00
100 G
CHF 1’390.00

CHF 250.00


Voraussichtliches Versanddatum07. April 2025


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5 G
CHF 250.00
25 G
CHF 427.00
100 G
CHF 1’390.00

About This Item

Lineare Formel:
HOOCCH2COCOOH
CAS-Nummer:
Molekulargewicht:
132.07
Beilstein:
1705475
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352204
PubChem Substanz-ID:
NACRES:
NA.75

CHF 250.00


Voraussichtliches Versanddatum07. April 2025


Bulk-Bestellung anfordern

Biologische Quelle

synthetic (organic)

Qualitätsniveau

Produktlinie

BioReagent

Assay

≥97% (HPLC)

Form

powder

Methode(n)

cell culture | insect: suitable
cell culture | mammalian: suitable

Löslichkeit

H2O: 100 mg/mL

Lagertemp.

−20°C

SMILES String

OC(=O)CC(=O)C(O)=O

InChI

1S/C4H4O5/c5-2(4(8)9)1-3(6)7/h1H2,(H,6,7)(H,8,9)

InChIKey

KHPXUQMNIQBQEV-UHFFFAOYSA-N

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Allgemeine Beschreibung

Oxaloacetic acid is a dicarboxylic acid that is present in every cell in the body. It is a metabolic intermediate of the tricarboxylic acid (TCA) cycle and gluconeogenesis.

Anwendung

Oxaloacetic acid has been used to evaluate its effect on neuromuscular function and lifespan in amyotrophic lateral sclerosis (ALS) model superoxide dismutase 1 (SOD1) G93A mice. It has also been used as a supplement in Dulbecco′s modified Eagle′s medium (DMEM) to culture chicken fibroblast (DF-1) cells and chemically immortalized leghorn male hepatoma (LMH) cells for functional validation experiments.

Biochem./physiol. Wirkung

Oxaloacetic acid plays a vital role in central metabolism. It inhibits succinate dehydrogenase and is a key regulator of mitochondrial metabolism.

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Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Eye Irrit. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Zhitao Wang et al.
Viruses, 13(6) (2021-07-03)
Gallid alpha-herpesvirus 1, also known as avian infectious laryngotracheitis virus (ILTV), continues to cause huge economic losses to the poultry industry worldwide. Similar to that of other herpesvirus-encoded proteins, the expression of viral genes encoded by ILTV is regulated by
Brian D Fink et al.
The Journal of biological chemistry, 293(51), 19932-19941 (2018-11-06)
We recently reported a previously unrecognized mitochondrial respiratory phenomenon. When [ADP] was held constant ("clamped") at sequentially increasing concentrations in succinate-energized muscle mitochondria in the absence of rotenone (commonly used to block complex I), we observed a biphasic, increasing then
E Esenmo et al.
The American journal of physiology, 263(1 Pt 1), E36-E41 (1992-07-01)
Estimating the rate of hepatic gluconeogenesis in vivo from the incorporation of 14C from 14CO2 into glucose requires determination of the rates in liver of equilibration of oxaloacetate with fumarate, conversion of oxaloacetate to phosphoenolpyruvate (PEP), and conversion of PEP
Eva Brekke et al.
Glia, 60(1), 147-158 (2011-11-05)
Pyruvate carboxylation (PC) is thought to be the major anaplerotic reaction for the tricarboxylic acid cycle and is necessary for de novo synthesis of amino acid neurotransmitters. In the brain, the main enzyme involved is pyruvate carboxylase, which is predominantly
Anthony Gandin et al.
Plant & cell physiology, 53(9), 1627-1637 (2012-08-01)
In higher plants, the mitochondrial electron transport chain has non-phosphorylating alternative pathways that include the alternative terminal oxidase (AOX). This alternative pathway has been suggested to act as a sink for dissipating excess reducing power, minimizing oxidative stress and possibly

Questions

  1. Is oxaloacetate The same as ox bile?

    1 answer
    1. No, this product is not the same as Ox Bile. The two materials are unrelated. See the link below to review availabe Ox Bile products:
      https://www.sigmaaldrich.com/product/sial/70168

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