D7159

2′,3′-Dideoxycytidine 5′-triphosphate sodium salt

≥90% (HPLC)

• Synonym(e): ddCTP
• Empirische Formel (Hill-System): C₉H₁₆N₃O₁₂P₃
• CAS-Nummer: 132619-66-0
• Molekulargewicht: 451.16
• MDL-Nummer: MFCD00717536
• UNSPSC-Code: 12352202
• PubChem Substanz-ID: 24894086

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Assay: ≥90% (HPLC)
• Form: powder
• Löslichkeit: water: 1 mg/mL, clear, colorless
• Lagertemp.: −20°C
• SMILES String: [Na+].NC1=NC(=O)N(C=C1)[C@H]2CC[C@@H](COP([O-])(=O)OP(O)(=O)OP(O)(O)=O)O2
• InChI: 1S/C9H16N3O12P3.Na/c10-7-3-4-12(9(13)11-7)8-2-1-6(22-8)5-21-26(17,18)24-27(19,20)23-25(14,15)16;/h3-4,6,8H,1-2,5H2,(H,17,18)(H,19,20)(H2,10,11,13)(H2,14,15,16);/q;+1/p-1/t6-,8+;/m0./s1
• InChIKey: LOOMQRBEBYCFPP-QDOHZIMISA-M

Beschreibung

Anwendung

Complexes of ddCTP with DNA polymerase β were studied by x-ray crystallography, with implications for inhibitory activity against HIV reverse transcriptase.

Biochem./physiol. Wirkung

Inhibitor von DNA-Polymerase I-katalysierter Kettenverlängerung.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)