A0760

L-Azetidin-2-Carboxylsäure

≥99%

• Synonym(e): (S)-Azetidin-2-carbonsäure
• Empirische Formel (Hill-System): C₄H₇NO₂
• CAS-Nummer: 2133-34-8
• Molekulargewicht: 101.10
• Beilstein: 80680
• EG-Nummer: 218-362-5
• MDL-Nummer: MFCD00005166
• UNSPSC-Code: 12352209
• PubChem Substanz-ID: 24278205
• NACRES: NA.32

Eigenschaften

• Assay: ≥99%
• Form: powder
• SMILES String: OC(=O)[C@@H]1CCN1
• InChI: 1S/C4H7NO2/c6-4(7)3-1-2-5-3/h3,5H,1-2H2,(H,6,7)/t3-/m0/s1
• InChIKey: IADUEWIQBXOCDZ-VKHMYHEASA-N

Beschreibung

Allgemeine Beschreibung

L-Azetidine-2-carboxylic acid is a non-protein amino acid and teratogenic agent. It is toxic in nature.[1]

Anwendung

L-Azetidine-2-carboxylic acid has been used as a:

• collagen synthesis inhibitor[2]
• protein folding antagonist[3]
• as a standard in liquid chromatography-mass spectrometry[1]

Biochem./physiol. Wirkung

L-Azetidine-2-carboxylic acid is an inhibitor of collagen synthesis that is anti-angiogenic.

Vierring-Analog des L-Prolins

Azetidine-2-carboxylic acid (AZC) triggers protein aggregation or upregulates the expression of an aggregation-prone mutant protein, upon interference with nascent protein folding.[4][5]

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)