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Sigma-Aldrich

Thiazolylblau-formazan

MTT reduction end product, powder

Synonym(e):

1-(4,5-Dimethylthiazol-2-yl)-3,5-diphenylformazan, MTT-Formazan

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About This Item

Empirische Formel (Hill-System):
C18H17N5S
CAS-Nummer:
57360-69-7
Molekulargewicht:
335.43
MDL-Nummer:
MFCD00080731
UNSPSC-Code:
12352204
PubChem Substanz-ID:
329769650
NACRES:
NA.83

product name

Thiazolylblau-formazan, MTT reduction end product

Form

powder

Löslichkeit

chloroform: 10 mg/mL, clear, dark violet

SMILES String

Cc1nc(\N=N\C(=N\Nc2ccccc2)c3ccccc3)sc1C

InChI

1S/C18H17N5S/c1-13-14(2)24-18(19-13)23-22-17(15-9-5-3-6-10-15)21-20-16-11-7-4-8-12-16/h3-12,20H,1-2H3/b21-17+,23-22+

InChIKey

GIFKVQOPAJDJLO-SZVLODPRSA-N

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Anwendung

MTT Formazan has been used in cell viability assay.

Biochem./physiol. Wirkung

MTT assay is a colorimetric reaction, generally used to examine cell viability. It involves the enzymatic reduction of a yellow-colored, water-soluble, 3-[4,5-dimethylthiazole-2-yl]-2,5-diphenyltetrazolium bromide (MTT) to purple-colored, water-insoluble, MTT-formazan. This reaction is catalyzed by mitochondrial dehydrogenase and only occurs in viable cells. Thus, the amount of blue formazan is proportional to the number of viable cells. The absorbance of the formazan solution is analyzed spectrophotometrically at 570 nm.

Sonstige Hinweise

Reviews: Tetrazolium salts and formazans

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Produkt-Nr.
Beschreibung
Preisangaben

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

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