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Merck

314R-1

Sigma-Aldrich

Cytokeratin 14 (SP53) Rabbit Monoclonal Antibody

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100
500

Konjugat

unconjugated

Antikörperform

culture supernatant

Antikörper-Produkttyp

primary antibodies

Klon

SP53, monoclonal

Beschreibung

For In Vitro Diagnostic Use in Select Regions (See Chart)

Form

buffered aqueous solution

Speziesreaktivität

human

Verpackung

vial of 0.1 mL concentrate (314R-14)
vial of 0.5 mL concentrate (314R-15)
bottle of 1.0 mL predilute (314R-17)
vial of 1.0 mL concentrate (314R-16)
bottle of 7.0 mL predilute (314R-18)

Hersteller/Markenname

Cell Marque

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Isotyp

IgG

Kontrolle

squamous carcinoma

Versandbedingung

wet ice

Lagertemp.

2-8°C

Visualisierung

cytoplasmic

Angaben zum Gen

human ... KRT14(3861)

Allgemeine Beschreibung

Cytokeratin 14 is a 50 kDa polypeptide found in basal cells of squamous epithelia, some glandular epithelia, myoepithelium, and mesothelial cells. Anti-CK14 is expressed in most squamous cell carcinomas, in epithelioid mesothelioma, and in the basal-like phenotype of breast carcinoma.
Anti-CK14 has been demonstrated to be useful in differentiating squamous cell carcinomas from other epithelial tumors. This antibody has also been useful in separating oncocytic tumors of the kidney from its renal mimics, as well as in identifying metaplastic carcinomas of the breast. Anti-CK14 is particularly valuable in identifying basal-like carcinoma of the breast.

Qualität


IVD

IVD

IVD

RUO

Verlinkung

Cytokeratin 14 Positive Control Slides, Product No. 314S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Angaben zur Herstellung

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Rechtliche Hinweise

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Diagnostic Immunohistochemistry: Theranostic and Genomic Applications, 166-176 (2002)
P G Chu et al.
Histopathology, 39(5), 455-462 (2001-12-12)
The cytokeratin 14 (CK14) expression in oncocytomas or oncocytic tumours of various tissue origins has not been established. We have studied CK14 expression in 30 cases of oncocytic tumours of various tissue origins and 33 cases of renal cell carcinoma
Jorge S Reis-Filho et al.
Applied immunohistochemistry & molecular morphology : AIMM, 11(1), 1-8 (2003-03-01)
Metaplastic carcinomas of the breast (MCBs) are unusual neoplasms characterized by an admixture of glandular epithelial components, which frequently exhibit features of squamous differentiation, and mesenchymal malignant components. Regardless of the presence of myoepithelial features in MCB, no consensus concerning
P G Chu et al.
Histopathology, 39(1), 9-16 (2001-07-17)
The tissue distribution of cytokeratin 14 (CK14) in epithelial neoplasms is not well defined. We have evaluated 435 cases of epithelial neoplasm of various origins with cytokeratin 14 monoclonal antibody with special attention to possible use in differential diagnosis. Immunohistochemistry

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