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Merck

21966

Sigma-Aldrich

5(6)-Carboxy-X-rhodamin-N-succinimidylester

BioReagent, suitable for fluorescence

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About This Item

Empirische Formel (Hill-System):
C37H33N3O7
CAS-Nummer:
Molekulargewicht:
631.67
UNSPSC-Code:
12352200
PubChem Substanz-ID:

Produktlinie

BioReagent

Löslichkeit

DMF: soluble
acetonitrile: soluble

Fluoreszenz

λex 575 nm; λem 605 nm in 0.1 M phosphate pH 7.0

Eignung

suitable for fluorescence

Lagertemp.

−20°C

SMILES String

O=C1CCC(=O)N1OC(=O)c2ccc3c(c2)C(=O)OC34c5cc6CCCN7CCCc(c5Oc8c9CCCN%10CCCc(cc48)c9%10)c67.O=C%11CCC(=O)N%11OC(=O)c%12ccc%13C(=O)OC%14(c%15cc%16CCCN%17CCCc(c%15Oc%18c%19CCCN%20CCCc(cc%14%18)c%19%20)c%16%17)c%13c%12

InChI

1S/2C37H33N3O7/c41-29-11-12-30(42)40(29)47-35(43)22-9-10-26-25(17-22)36(44)46-37(26)27-18-20-5-1-13-38-15-3-7-23(31(20)38)33(27)45-34-24-8-4-16-39-14-2-6-21(32(24)39)19-28(34)37;41-29-11-12-30(42)40(29)47-35(43)22-9-10-23-26(19-22)37(46-36(23)44)27-17-20-5-1-13-38-15-3-7-24(31(20)38)33(27)45-34-25-8-4-16-39-14-2-6-21(32(25)39)18-28(34)37/h2*9-10,17-19H,1-8,11-16H2

InChIKey

YEWCZAUCUAYJIO-UHFFFAOYSA-N

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Anwendung

5(6)-Carboxy-X-rhodamine N-succinimidyl ester may used as a labeling reagent to attach the fluorophore 5(6)-carboxy-X-rhodamine to target molecules such as nucleic acids. 5(6)-Carboxy-X-rhodamine labeled molecules may be used in fluorescence energy transfer (FRET) applications.

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

S C Hung et al.
Analytical biochemistry, 255(1), 32-38 (1998-02-04)
Fluorescence energy transfer (ET) primers are far superior to single dye-labeled primers as labels for DNA sequencing and polymerase chain reaction amplification. We compare here ET primers with different donor and acceptor dye combinations with respect to the relative acceptor
S C Hung et al.
Analytical biochemistry, 252(1), 78-88 (1997-11-05)
We have synthesized and characterized the spectroscopic properties of 56 energy transfer (ET) fluorescent dye-labeled primers differing in (i) the spacing between the donor and acceptor, (ii) the nature of the spacer (either oligonucleotide or polydideoxyribose phosphate), (iii) the primer
Tae Seok Seo et al.
Proceedings of the National Academy of Sciences of the United States of America, 102(17), 5926-5931 (2005-04-15)
We report four-color DNA sequencing by synthesis (SBS) on a chip, using four photocleavable fluorescent nucleotide analogues (dGTP-PC-Bodipy-FL-510, dUTP-PC-R6G, dATP-PC-ROX, and dCTP-PC-Bodipy-650) (PC, photocleavable; Bodipy, 4,4-difluoro-4-bora-3alpha,4alpha-diaza-s-indacene; ROX, 6-carboxy-X-rhodamine; R6G, 6-carboxyrhodamine-6G). Each nucleotide analogue consists of a different fluorophore attached to
Hailong Li et al.
Biosensors & bioelectronics, 27(1), 167-171 (2011-07-26)
In this article, we report on the first use of fluorescence resonance energy transfer (FRET) dye-labeled probe for fluorescence resonance enhanced DNA detection to greatly improve discrimination ability toward single-base mismatch using conjugation polymer poly(p-phenylenediamine) nanobelts (PNs) as a sensing

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