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Merck

M8054

Sigma-Aldrich

Mangan(II)-chlorid Tetrahydrat

meets USP testing specifications

Synonym(e):

Manganese chloride hydrate, Manganese chloride tetrahydrate, MnCl2.4H2O

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About This Item

Lineare Formel:
MnCl2 · 4H2O
CAS-Nummer:
Molekulargewicht:
197.91
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352302
PubChem Substanz-ID:
NACRES:
NA.21

Agentur

USP/NF
meets USP testing specifications

Qualitätsniveau

Assay

98.0-101.0% dry basis

Form

flakes

mp (Schmelzpunkt)

58 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

SMILES String

Cl[Mn]Cl.[H]O[H].[H]O[H].[H]O[H].[H]O[H]

InChI

1S/2ClH.Mn.4H2O/h2*1H;;4*1H2/q;;+2;;;;/p-2

InChIKey

CNFDGXZLMLFIJV-UHFFFAOYSA-L

Verwandte Kategorien

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Oral - Eye Dam. 1 - STOT RE 2

Zielorgane

Brain

Lagerklassenschlüssel

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 2

Flammpunkt (°F)

does not flash

Flammpunkt (°C)

does not flash

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Lisha Luo et al.
NMR in biomedicine, 25(12), 1360-1368 (2012-05-11)
The aim of this study was to provide data on the dose dependence of manganese-enhanced MRI (MEMRI) in the visual pathway of experimental rats and to study the toxicity of MnCl₂ to the retina. Sprague-Dawley rats were intravitreally injected with
Marta Sidoryk-Wegrzynowicz et al.
Journal of neurochemistry, 122(4), 856-867 (2012-06-20)
Manganese (Mn) has been implicated in the impairment of the glutamate-glutamine cycling (GGC) by deregulation of Glu and glutamine (Gln) turnover in astrocytes. Here, we have examined possible mechanisms involved in the Mn(II)-mediated disruption of Glu turnover, including those related
Jerome A Roth et al.
Neurotoxicology, 35, 121-128 (2013-01-15)
Chronic exposure to Mn results in the development of a neurological disorder known as manganism characterized by neurological deficits resembling that seen in Parkinsonism. Although dopaminergic neurons within the nigrostriatal pathway appear intact, Mn-induced irregularities in DA transmission have been
Tameshwar Ganesh et al.
Journal of magnetic resonance imaging : JMRI, 41(3), 806-813 (2014-03-05)
To investigate the potential of manganese (Mn)-enhanced MRI for sensitive detection and delineation of tumors that demonstrate little enhancement on Gd-DTPA. Eighteen nude rats bearing 1 to 2 cm in diameter orthotopic breast tumors (ZR75 and LM2) were imaged on
Anne Bertrand et al.
NeuroImage, 64, 693-702 (2012-09-11)
The impairment of axonal transport by overexpression or hyperphosphorylation of tau is well documented for in vitro conditions; however, only a few studies on this phenomenon have been conducted in vivo, using invasive procedures, and with contradictory results. Here we

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