Mucins are soluble in water, forming hazy viscous solutions.
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M1778
Mucin aus Schweinemagen
Type III, bound sialic acid 0.5-1.5 %, partially purified powder
Synonym(e):
MUC
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10 G
CHF 95.90
100 G
CHF 479.00
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10 G
CHF 95.90
100 G
CHF 479.00
About This Item
Empfohlene Produkte
Biologische Quelle
Porcine stomach
Qualitätsniveau
Typ
Type III
Form
partially purified powder
Zusammensetzung
bound sialic acid, 0.5-1.5%
Methode(n)
microbiological culture: suitable
Löslichkeit
NaOH: soluble 20 mg/mL
Lagertemp.
2-8°C
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Allgemeine Beschreibung
Anwendung
Mucin wurde in Studien über den Bindungssitus des galaktosespezifischen Agglutinins PA-IL von Pseudomonas aeruginosa verwendet.[3]
Biochem./physiol. Wirkung
Mukosa (Schleimhaut) bildet auf allen Epitheloberflächen eine Schutzschicht. Struktureller Hauptbestandteil von Schleim sind gelbildende Mucine. In der das Darmepithel bedeckenden Schleimschicht ist das MUC2-Mucin das zentrale Molekül. MUC2 wird von den Becherzellen produziert.[4]
Angaben zur Herstellung
Hergestellt gemäß dem Verfahren nach Glenister, et al. für die Verwendung in komplexen Kulturmedien für dentale Plaque-Bakterien.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Analysenzertifikate (COA)
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Artikel
Understand sialic acid structure, function, signaling, and modifications. Easily find products for sialic acid research.
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Can I reconstitute the mucin so that it forms a saliva/snot-like substance? I can't seem to find any papers that have done this...
1 answer-
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How can I solubilize Product M1778, Mucin from porcine stomach?
1 answer-
Mucin is not readily soluble in aqueous solutions. Turbid "solutions" will form at about 5 mg/mL in 0.1 M acetate buffer, pH 5.0. To try to increase the solubility, one might try further dilution and sonication, but we have not tried this in our labs.
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What does the "Type" designation in Mucin from porcine stomach mean?
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The type designation does not have any particular biological significance. It is used to emphasize differences in the listings of this product.
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What is the molecular weight of Product M1778, Mucin from porcine stomach?
1 answer-
This product is partially purified from crude mucin, M2378. Sigma has not determined the molecular weight of this product. Neither has the sugar and amino acid composition been determined.
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What is the Department of Transportation shipping information for this product?
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Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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What are the differences between Mucin from porcine stomach Products M2378 and M1778?
1 answer-
Product No. M2378 is a crude mucin preparation. Product No. M1778 is a partially purified powder prepared according to the method described in Glenister, D.A. and Salmon. K. Microbial Ecol. in Health & Disease 1, 31, (1988). The amount of bound sialic acids are also different. Please refer to the specification sheets on our website.
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Is Product M1778, Mucin from porcine stomach, a purified preparation of mucin?
1 answer-
This product is a partially purified preparation of mucin based on the method of Glenister cited on the product's webpage.
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