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Merck

8.05740

Sigma-Aldrich

2-Mercaptoethanol

for synthesis

Synonym(e):

Hydroxyethylmercaptan, Thioethylenglycol, Thioglycol, β-Mercaptoethanol, 2-Hydroxyethylmercaptan, BME, Thioethylenglycol

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5 ML
CHF 26.60
250 ML
CHF 44.50
1 L
CHF 110.00
25 L
CHF 1’090.00

CHF 26.60


Voraussichtliches Versanddatum23. Mai 2025


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5 ML
CHF 26.60
250 ML
CHF 44.50
1 L
CHF 110.00
25 L
CHF 1’090.00

About This Item

Lineare Formel:
HSCH2CH2OH
CAS-Nummer:
Molekulargewicht:
78.13
Beilstein:
773648
MDL-Nummer:
UNSPSC-Code:
12352104
EG-Index-Nummer:
200-464-6
NACRES:
NA.22

CHF 26.60


Voraussichtliches Versanddatum23. Mai 2025


Bulk-Bestellung anfordern

Dampfdichte

2.69 (vs air)

Qualitätsniveau

Dampfdruck

1 mmHg ( 20 °C)

Assay

≥99% (GC)

Form

liquid

Selbstzündungstemp.

295 °C

Wirksamkeit

98-162 mg/kg LD50, oral (Rat)
112-224 mg/kg LD50, skin (Rabbit)

Expl.-Gr.

18 %

Eignung der Reaktion

reagent type: reductant

Konzentration

14.3 M (pure liquid)

Brechungsindex

n20/D 1.500 (lit.)

pH-Wert

4.5-6 (20 °C, 500 g/L in H2O)

bp

157 °C (lit.)

mp (Schmelzpunkt)

<-50 °C

Übergangstemp.

flash point 70.5 °C

Dichte

1.114 g/mL at 25 °C (lit.)

Lagertemp.

2-30°C

SMILES String

OCCS

InChI

1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2

InChIKey

DGVVWUTYPXICAM-UHFFFAOYSA-N

Anwendung

BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1A - STOT RE 2 Oral

Lagerklassenschlüssel

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flammpunkt (°F)

165.2 °F - closed cup

Flammpunkt (°C)

74 °C - closed cup


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Georg Michlits et al.
Nature methods, 17(7), 708-716 (2020-06-10)
CRISPR-Cas9 screens have emerged as a transformative approach to systematically probe gene functions. The quality and success of these screens depends on the frequencies of loss-of-function alleles, particularly in negative-selection screens widely applied for probing essential genes. Using optimized screening

Questions

1–3 of 3 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. Bonjour,  Utilisant le b2 mercaptoethanol en laboratoire, je souhaiterais savoir quel masque vous préconisez lors de la manipulation du produit. Merci. Cordialement 

    1 answer
    1. According to page 6 of the Safety Data Sheet, a 'Filter B-(P3)' mask is recommended.

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