76172

O-(2-Aminoethyl)-O′-(2-azidoethyl)-pentaethyleneglykol

≥90% (oligomer purity)

• Synonym(e): Azido-PEG-amin (n=6)
• Empirische Formel (Hill-System): C₁₄H₃₀N₄O₆
• CAS-Nummer: 957486-82-7
• Molekulargewicht: 350.41
• MDL-Nummer: MFCD03453240
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 57652623
• NACRES: NA.22

Eigenschaften

• Assay: ≥90% (oligomer purity)
• Form: liquid
• Eignung der Reaktion: reaction type: click chemistry; reagent type: cross-linking reagent
• Funktionelle Gruppe: amine; azide
• Lagertemp.: 2-8°C
• SMILES String: NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-]
• InChI: 1S/C14H30N4O6/c15-1-3-19-5-7-21-9-11-23-13-14-24-12-10-22-8-6-20-4-2-17-18-16/h1-15H2
• InChIKey: VCQSTKKJKNUQBI-UHFFFAOYSA-N

Beschreibung

Anwendung

O-(2-Aminoethyl)-O′-(2-azidoethyl)pentaethylene glycol can be used:

• As a reactant for the synthesis of thin films of azide functionalized poly(L-glutamic acid) for drug delivery.
• For the synthesis of curcumin monoazide derivatives for fabricating biologically active curcumin conjugates.
• To modify the surface of TiO₂ nanoparticles to attach DNA strands for photocatalytic reduction of CO₂.
• For the conjugation of poly(ethylene glycol) (PEG) with toll-like receptor 7 (TLR7) to improve its pharmaceutical properties.

O-(2-Aminoethyl)-O′-(2-azidoethyl)pentaethylene glycol has been used in the synthesis of Alexa568-azide, a fluorescent azide that can undergo click staining reaction with 5-ethynyluridine-labeled cellular RNA.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315 - H319 - H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type ABEK (EN14387) respirator filter