682144

(R)-(-)-4,12-Bis(diphenylphosphino)-[2.2]-Paracyclophan

96%

• Synonym(e): (R)-Phanephos
• Empirische Formel (Hill-System): C₄₀H₃₄P₂
• CAS-Nummer: 364732-88-7
• Molekulargewicht: 576.65
• MDL-Nummer: MFCD03094575
• UNSPSC-Code: 12352002
• PubChem Substanz-ID: 24885681
• NACRES: NA.22

Eigenschaften

• Assay: 96%
• Form: solid
• Optische Aktivität: [α]/D -34±4°, c = 1 in chloroform
• mp (Schmelzpunkt): 222-226 °C
• InChI: 1S/C40H34P2/c1-5-13-35(14-6-1)41(36-15-7-2-8-16-36)39-29-31-21-25-33(39)27-23-32-22-26-34(28-24-31)40(30-32)42(37-17-9-3-10-18-37)38-19-11-4-12-20-38/h1-22,25-26,29-30H,23-24,27-28H2
• InChIKey: GYZZZILPVUYAFJ-UHFFFAOYSA-N

Beschreibung

Anwendung

Efficient ligand for asymmetric hydrogentation of dehydroamino acids, methyl esters and keytones.

(R)-(-)-4,12-Bis(diphenylphosphino)-[2.2]-paracyclophane may be used as a ligand in the following processes:

• Enantioselective reductive cyclization of 1,6-enynes via asymmetric hydrogenation in the presence of a rhodium catalyst to form alkylidene-substituted heterocycles.
• Asymmetric hydroboration of 3,3-disubstituted cyclopropenes to form 2,2-disubstituted cyclopropyl boronates.
• Asymmetric ring-opening reactions of azabenzonorbornadienes in the presence of zinc(II) triflate and palladium(II) acetate to form aminodihydronaphthalenes.

Rechtliche Hinweise

Sold in collaboration with Johnson Matthey Catalyst for research purposes only. US5874629 and any patents arising therefrom apply.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves