666467

Indol-5-boronsäure

≥95%

• Synonym(e): 5-Indolboronsäure, 5-Indolylboronsäure
• Lineare Formel: (C₈H₆N)B(OH)₂
• CAS-Nummer: 144104-59-6
• Molekulargewicht: 160.97
• MDL-Nummer: MFCD01319013
• UNSPSC-Code: 12352103
• PubChem Substanz-ID: 24884799
• NACRES: NA.22

Eigenschaften

• Assay: ≥95%
• Form: solid
• mp (Schmelzpunkt): 170-175 °C
• Lagertemp.: 2-8°C
• SMILES String: OB(O)c1ccc2[nH]ccc2c1
• InChI: 1S/C8H8BNO2/c11-9(12)7-1-2-8-6(5-7)3-4-10-8/h1-5,10-12H
• InChIKey: VHADYSUJZAPXOW-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

May contain varying amounts of anhydride

Anwendung

Reactant involved in the synthesis of biologically active molecules including:

• Indole inhibitors of MMP-13 for arthritic disease treatment
• Substituted pyrimidines acting as tubulin polymerization inhibitors

Reactant involved in Suzuki coupling reactions for synthesis of

• Aryl- hetarylfurocoumarins
• Aryl-substituted oxabenzindoles and methanobenzindoles

Reactant involved in:

• Oxidative cross-coupling with mercaptoacetylenes
• Trifluoromethylation

Substrate used in a rhodium-catalyzed 1,4-addition to unprotected maleimides.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves