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189871

Sigma-Aldrich

Ethylmagnesiumbromid -Lösung

3.0 M in diethyl ether

Synonym(e):

EtMgBr-Lösung

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About This Item

Lineare Formel:
CH3CH2MgBr
CAS-Nummer:
Molekulargewicht:
133.27
Beilstein:
3587203
MDL-Nummer:
UNSPSC-Code:
12352103
PubChem Substanz-ID:
NACRES:
NA.22
Preise und Verfügbarkeit sind derzeit nicht verfügbar.

Form

liquid

Qualitätsniveau

Eignung der Reaktion

reaction type: Grignard Reaction

Konzentration

3.0 M in diethyl ether

bp

34.6 °C/1.013  hPa

Dichte

1.02 g/mL at 25 °C

SMILES String

[CC[Mg]Br]
CC[Mg]Br

InChI

[1S/C2H5.BrH.Mg/c1-2;;/h1H2,2H3;1H;/q;;+1/p-1]
1S/C2H5.BrH.Mg/c1-2;;/h1H2,2H3;1H;/q;;+1/p-1

InChIKey

[HSNUIYJWTSJUMS-UHFFFAOYSA-N]
TWTWFMUQSOFTRN-UHFFFAOYSA-M

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Allgemeine Beschreibung

Ethylmagnesiumbromid, eine Organomagnesiumverbindung, ist allgemein als Grignard-Reagenz bekannt.[1] Es ist ein starkes Kohlenstoffnukleophil, das hauptsächlich zur Bildung von C-C-Bindungen eingesetzt wird.[2]

Anwendung

Ethylmagnesiumbromid-Lösung (3,0 M in Diethylether) kann für Kupfer(I)-katalysierte Allylsubstitutionsreaktionen verwendet werden.[2]

Verpackung

Die 25-ml-Sure/Seal Flasche wird für den Einmalgebrauch empfohlen. Wiederholte Einstiche führen höchstwahrscheinlich zu einer Leistungsminderung des Produkts.

Rechtliche Hinweise

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 1 - Skin Corr. 1B - STOT SE 3 - Water-react 1

Zielorgane

Respiratory system

Zusätzliche Gefahrenhinweise

Lagerklassenschlüssel

4.3 - Hazardous materials which set free flammable gases upon contact with water

WGK

WGK 1

Flammpunkt (°F)

-40.0 °F - closed cup

Flammpunkt (°C)

-40 °C - closed cup

Persönliche Schutzausrüstung

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


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Analysenzertifikate (COA)

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Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Enantioselective Copper-Catalyzed SN2? Substitution with Grignard Reagents.
Alexakis A, et al.
Synlett, 0927-0930 (2001)
Organic Chemistry, 542-542 (2008)
T Nishiyama et al.
Chemical & pharmaceutical bulletin, 48(12), 1999-2002 (2001-01-06)
The direct alpha-bromination of various ketones using trifluoromethanesulfonic anhydride and Grignard reagent or magnesium bromide in ether gave the corresponding alpha-bromo ketones in moderate to good yields under mild reaction conditions.
F Turon et al.
Lipids, 37(8), 817-821 (2002-10-10)
An analytical procedure was developed for regiodistribution analysis of TAG using alpha-MAG prepared by an ethyl magnesium bromide deacylation. In the present communication, the deacylation procedure is shown to lead to representative alpha-MAG, allowing the composition of the native TAG
Janne E Tønder et al.
Organic & biomolecular chemistry, 2(10), 1447-1455 (2004-05-12)
Copper mediated allylic substitutions and conjugate additions to geranyl, cinnamyl and allylic indole compounds have been investigated with the aim of finding a method for the creation of the all-carbon quaternary centre present in the natural product lyngbyatoxin A. Reaction

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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