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HTR4

5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

Synonyme:
5-HT4, 5-HT4R
Spezies:
Human HTR4 (3360), Mouse Htr4 (15562), Rat Htr4 (25324), Horse HTR4 (100034053), domestic cat HTR4 (101088723), sheep HTR4 (101117928), cow HTR4 (317708), domestic guinea pig Htr4 (100135548), chicken HTR4 (416150), dog HTR4 (489198)
UniProtKB-ID:
Q13639, Q546Q1, Q684M0, Q712M9, Q96KH9, Q96KI0, Q9H199, Q9NY73
Gen-ID:
  • Human(3360) Summary: This gene is a member of the family of serotonin receptors, which are G protein coupled receptors that stimulate cAMP production in response to serotonin (5-hydroxytryptamine). The gene product is a glycosylated transmembrane protein that functions in both the peripheral and central nervous system to modulate the release of various neurotransmitters. Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described. [provided by RefSeq, May 2010]
  • Mouse(15562) 5 hydroxytryptamine (serotonin) receptor 4
  • Rat(25324) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • Horse(100034053) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • domestic cat(101088723) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • sheep(101117928) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • cow(317708) 5-hydroxytryptamine (serotonin) receptor 4
  • domestic guinea pig(100135548) 5 hydroxytryptamine (serotonin) receptor 4
  • chicken(416150) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • dog(489198) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
  • naked mole-rat(101707865) 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
SML1504
Tegaserod maleate, ≥98% (HPLC),
Spezies
human
32473
Metoclopramid, VETRANAL®, analytical standard,
Spezies
human
BP357
Metoclopramid -hydrochlorid, British Pharmacopoeia (BP) Reference Standard,
Spezies
human
M1824990
Metoclopramid, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
M0763
Metoclopramid -hydrochlorid, solid,
Spezies
human

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
D9190
DCEBIO, ≥98% (HPLC), solid,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
S3313
SB-204070 hydrochloride, solid, ≥97% (HPLC),
Spezies
human
M7319
ML 10302, ≥98%, solid,
Spezies
rat
G5918
GR 113808, ≥98% (HPLC), solid,
Spezies
rat, human
32473
Metoclopramid, VETRANAL®, analytical standard,
Spezies
human
BP357
Metoclopramid -hydrochlorid, British Pharmacopoeia (BP) Reference Standard,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
SAB4501480
Anti-5-HT-4 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human, mouse, rat
Anwendung
ELISA
immunofluorescence
western blot
HPA040591
Anti-HTR4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
SAB2101109
Anti-HTR4 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
dog, human, rabbit
Anwendung
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
T3146
Trimipramin -maleat (Salz), ≥98% (TLC), powder,
Spezies
human
Z101
Zimelidin -dihydrochlorid, solid,
Spezies
human

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Spezies
human
F1678
R-(−)-Fluoxetin -hydrochlorid, >98% (HPLC), solid,
Spezies
human
F132
Fluoxetin -hydrochlorid, solid,
Spezies
human
R0875
Reserpin, ,
Spezies
human
S6319
Sertralin -hydrochlorid, ≥98% (HPLC),
Spezies
human

Small Molecule - Ligand

Produktnummer
Beschreibung
Spezies
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Spezies
human

Small Molecule - Metabolite

Produktnummer
Beschreibung
Spezies
H8876
5-Hydroxyindol-3-Essigsäure, ≥98% (HPLC), crystalline,
Spezies
human

Small Molecule - Precursor

Produktnummer
Beschreibung
Spezies
H9772
5-Hydroxy-L-Tryptophan, powder,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
EHU070651
MISSION® esiRNA, targeting human HTR4,
Spezies
human