P3513
Poly-L-lysine, succinylated
mol wt >50,000
Sinônimo(s):
Modified Lysine Copolymer
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About This Item
Produtos recomendados
forma
powder or solid
Nível de qualidade
peso molecular
>50,000
cor
white to faint yellow
aplicação(ões)
cell analysis
temperatura de armazenamento
−20°C
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Aplicação
Succinylated poly-L-lysine has been used to bind (Gly)3-Arg-bradykinin to study its hydrolysis by brain endopeptidases and pancreatic proteinases.
Ações bioquímicas/fisiológicas
Poly-L-lysine is a cationic polymer. It is mainly used for immobilizing cells to glass substrates or negatively charged substrates.
An intermediate for coupling proteins to poly-L-lysine.
Nota de análise
Molecular weight based on precursor poly-L-lysine viscosity. Also assayed by MALLS.
Outras notas
For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
Certificados de análise (COA)
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Cancer biotherapy & radiopharmaceuticals, 26(6), 727-736 (2011-11-18)
Avidin-coupled monoclonal antibody MX35 (avidin-MX35) and astatine-211-labeled, biotinylated, succinylated poly-l-lysine ((211)At-B-PL(suc)) were administered in mice to assess potential efficacy as an intraperitoneal (i.p.) therapy for microscopic tumors. We aimed to establish a timeline for pretargeted radioimmunotherapy using these substances, and
Effects of poly(L-lysine) substrates on attached Escherichia coli bacteria.
Langmuir, 26(4), 2639-2644 (2010)
Susceptibility of a Peptide Derived from Bradykinin to Hydrolysis by Brain Endo-oligopeptidases and Pancreatic Proteinases*
The Journal of Biological Chemistry, 254(12), 5304-5307 (1979)
British journal of cancer, 89(5), 937-943 (2003-08-28)
Conjugates between photosensitisers (PS) and charged polymeric carriers are under investigation for photodynamic therapy of cancer and may allow targeting to certain cell types or compartments in tumours. Covalent attachment of polyethylene glycol to macromolecules (pegylation) may alter their pharmacokinetics
Nucleic acids research, 27(15), 3090-3095 (1999-08-24)
DNA can be condensed with an excess of poly-cations in aqueous solutions forming stable particles of submicron size with positive surface charge. This charge surplus can be used to deposit alternating layers of polyanions and polycations on the surface surrounding
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