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L7414

Sigma-Aldrich

N-Lauroylsarcosine sodium salt solution

20%, for molecular biology

Sinônimo(s):

Sarcosyl, Sarkosyl NL, Sodium N-dodecanoyl-N-methylglycinate, Sodium N-lauroylsarcosinate solution

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About This Item

Fórmula linear:
CH3(CH2)10CON(CH3)CH2COONa
Número CAS:
Peso molecular:
293.38
Beilstein:
5322974
Número MDL:
Código UNSPSC:
12161900
ID de substância PubChem:
NACRES:
NA.25

grau

for molecular biology

Nível de qualidade

descrição

anionic

peso molecular

293.38 g/mol

concentração

19-21% (Titration by HClO4)
20%

atividade externa

DNase, RNase, and protease, none detected

cadeia de caracteres SMILES

[Na+].CCCCCCCCCCCC(=O)N(C)CC([O-])=O

InChI

1S/C15H29NO3.Na/c1-3-4-5-6-7-8-9-10-11-12-14(17)16(2)13-15(18)19;/h3-13H2,1-2H3,(H,18,19);/q;+1/p-1

chave InChI

KSAVQLQVUXSOCR-UHFFFAOYSA-M

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Descrição geral

N-Lauroylsarcosine sodium salt solution is an anionic surfactant which can be used in DNA extraction.

Aplicação

N-Lauroylsarcosine sodium salt has been used in a study to assess the mechanisms underlying surfactant-induced itching. It has also been used in a study to investigate the formation of pH-responsive, stable vesicles resulting from an interaction with N-cetylpyridinium chloride (CPC) and N-dodecylpyridinium chloride (DPC) in aqueous mixtures.

Características e benefícios

N-Lauroylsarcosine does not precipitate and is commonly used in place of SDS.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Eye Irrit. 2

Código de classe de armazenamento

10 - Combustible liquids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

512.6 °F

Ponto de fulgor (°C)

267 °C


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Interaction of sodium N-lauroylsarcosinate with N-alkylpyridinium chloride surfactants: Spontaneous formation of pH-responsive, stable vesicles in aqueous mixtures
Ghosh, S. and J. Dey
Journal of Colloid and Interface Science, 358, 9-9 (2011)
Alejandro Álvarez-Quilón et al.
Nature communications, 11(1), 910-910 (2020-02-16)
The ATM kinase is a master regulator of the DNA damage response to double-strand breaks (DSBs) and a well-established tumour suppressor whose loss is the cause of the neurodegenerative and cancer-prone syndrome Ataxia-Telangiectasia (A-T). A-T patients and Atm-/- mouse models
Takahiro Sekikawa et al.
New biotechnology, 29(1), 139-143 (2011-09-20)
Detection of low amounts of Cryptosporidium oocysts in raw water sources is considered an important component in the management, prevention and control of Cryptosporidium in drinking water supplies as Cryptosporidium causes massive waterborne outbreaks worldwide. As Cryptosporidium has a robust
Luoquan Li et al.
ACS sensors, 4(5), 1299-1305 (2019-05-03)
Droplet microfluidics-based platform (Drop-seq) has been shown to be a powerful tool for single cell expression profiling. Nevertheless, this platform required the simultaneous encapsulation of single cell and single barcoded bead, the incidence of which was very low, limiting its
Yoshihiro Inami et al.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 132(11), 1225-1230 (2012-11-06)
The primary function of surfactants is to remove dirt, exfoliated corneum cells, and microorganisms from the skin. However, the use of toiletries such as soaps and shampoos containing surfactants may cause adverse effects such as cutaneous irritation, dryness, and itching.

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