It is recommended that I7908 be reconstituted in 50mm Phosphate buffer, pH 7 containing 0.1 % BSA or HSA. Please see the link below the access the product datasheet for additional information:
https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/427/488/i7908dat.pdf
I7908
IL-2 human
≥98% (SDS-PAGE and HPLC), recombinant, expressed in Pichia pastoris, lyophiilized powder, suitable for cell culture
Sinônimo(s):
IL-2, Interleukin-2, T-cell growth factor
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10000 UNITS
R$ 2.034,00
R$ 2.034,00
Disponível para enviar em02 de abril de 2025Detalhes
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10000 UNITS
R$ 2.034,00
About This Item
R$ 2.034,00
Disponível para enviar em02 de abril de 2025Detalhes
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Nome do produto
Interleukin-2 human, recombinant, expressed in Pichia pastoris, suitable for cell culture
fonte biológica
human
Nível de qualidade
recombinante
expressed in Pichia pastoris
Ensaio
≥98% (SDS-PAGE and HPLC)
Formulário
lyophilized powder
peso molecular
predicted mol wt ~15 kDa
embalagem
pkg of 10KU
técnica(s)
cell culture | mammalian: suitable
Impurezas
endotoxin, tested
nº de adesão UniProt
Condições de expedição
dry ice
temperatura de armazenamento
−20°C
Informações sobre genes
human ... IL2(3558)
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Aplicação
Interleukin-2 human has been used to assess changes in tumor necrosis factor receptor 1 (TNFR1). It has also been used in TNFR2 expression on Tregs.[1]
Ações bioquímicas/fisiológicas
Interleukin 2 (IL2) is a pro-inflammatory cytokine.[2] It consists of three subunits, in which the β subunit is important for receptor mediated signaling.[3] IL2 enhances the development of T regulatory cells[4] and plays a crucial role in antitumor immunity.[2]
Interleukin-2 (IL-2) is an immunomodulatory factor produced by certain subsets of T lymphocytes. This lymphokine promotes long term growth of activated T cells and related cell types. IL-2 plays a role in the activation and proliferation of NK cells, induces γ-interferon and B cell growth factor secretion, and modulates the expression of the IL-2 receptor.
forma física
Lyophilized from a 0.2 μm filtered solution in 50 mM sodium phosphate buffer, pH 7.0, containing 0.1% human serum albumin per 0.1 mL of cytokine.
Nota de análise
The biological activity is tested in a cell proliferation assay using an IL-2 dependent murine cytotoxic T cell line, CTLL-2.
Código de classe de armazenamento
13 - Non Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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Tenemos IL-2 expresado en Pichia Pastoris desde hace un tiempo con esta referencia (I7908) sin reconstituir. Hemos perdido el data sheet y no sabemos en qué solución debemos reconstituirlo. Contacte conmigo para resolver nuestra duda.
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