I1645
Interleukin-8 human
≥98% (SDS-PAGE and HPLC), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Sinônimo(s):
IL-8
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About This Item
Produtos recomendados
fonte biológica
human
Nível de qualidade
recombinante
expressed in E. coli
Ensaio
≥98% (SDS-PAGE and HPLC)
forma
lyophilized powder
peso molecular
8.4 kDa
embalagem
pkg of 10 μg
técnica(s)
cell culture | mammalian: suitable
Impurezas
endotoxin, tested
nº de adesão UniProt
temperatura de armazenamento
−20°C
Informações sobre genes
human ... IL8(3576)
Aplicação
Interleukin-8 (IL-8) human has ben used to:
- measure neutrophil chemotoxis
- study the uptake of apoptotic cells by meningothelial cells
- study the effect of IL-8 on expression and secretion of urocortin-1 by human umbilical vein endothelial cells
Ações bioquímicas/fisiológicas
Interleukin-8 (IL-8) was formerly called monocyte-derived neutrophil chemotactic factor. It belongs to the chemokine α or C-X-C family. Like other members of this family, the mature form of IL-8 has four cysteine residues and the first two cysteine residues are separated by glutamine. IL-8 shows chemotactic activity in vitro for T cells, neutrophils and basophils. Mutation in IL-8 can increase risk to acute pancreatitis.
Interleukin-8 (IL-8), formerly called monocyte-derived neutrophil chemotactic factor, belongs to the chemokine α or C-X-C family. The mature form of IL-8 has 4 cysteine residues, as do the other members of the chemokine family and the first two cysteine residues are separated by glutamine. Mature human IL-8 consists of 72 amino acids with a molecular mass of 8.4 kDa. IL-8 exhibits chemotactic activity in vitro for T cells, basophils, as measured by enzymes including myeloperoxidase, α-mannosidase and β-glucuronidase. IL-8 is an angiogenic factor.
forma física
Lyophilized from a 0.2 μm filtered solution with no additives.
Nota de análise
The biological activity is determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 10.0-100.0 ng/ml.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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