I1521

DES (1-6) IGF II

lyophilized powder, recombinant, expressed in E. coli, suitable for cell culture

• Número CAS: 141909-47-9
• Número MDL: MFCD00285687
• Código UNSPSC: 12352202
• NACRES: NA.77

Propriedades

• fonte biológica: human
• recombinante: expressed in E. coli
• Ensaio: ≥95% (HPLC)
• Formulário: lyophilized powder
• potência: ≤100 ng/mL ED₅₀
• peso molecular: 6,765 Da
• embalagem: pkg of 20 μg
• condição de armazenamento: avoid repeated freeze/thaw cycles
• técnica(s): cell culture | mammalian: suitable
• Impurezas: endotoxin, tested
• cor: white
• nº de adesão UniProt: P01344
• temperatura de armazenamento: 2-8°C
• Informações sobre genes: human ... IGF2(3481)

Descrição

Descrição geral

DES (1-6) IGF-II is a 61 amino acid analog of human insulin-like growth factor II, lacking the first six N-terminal amimo acids. DES (1-6) IGF-II exhibits reduced affinity for IGF binding proteins (IGFBPs), which are known to inhibit the actions of IGF′s.

Aplicação

Used for studies of IGF-II function in cell culture applications. Use in combination with IGF-I, insulin and other forms of IGF-II to study receptor functions and cell signaling.

Outras notas

Recombinant analog of insulin-like growth factor II.

Nota de preparo

Prepared from 0.1 M acetic acid.

Synthesized recombinantly in E. coli using a patented fusion protein expression system, DES (1-6) IGF-II is then purified by liquid chromatography. DES (1-6) IGF-II has been developed as an inexpensive, high quality potent analog of IGF-II for use as a growth factor supplement in cell culture. DES (1-6) IGF-II is supplied as a powder, lyophilized from 0.1 M acetic acid. Molecular weight is 6,765 daltons.

Informações de segurança

• Código de classe de armazenamento: 13 - Non Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)