A7470
Anti-c-Myc Agarose Affinity Gel antibody produced in rabbit
affinity isolated antibody
Sinônimo(s):
Anti-c-Myc
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About This Item
Código UNSPSC:
12352203
NACRES:
NA.56
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![[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt ≥95% (HPLC), solid](/deepweb/assets/sigmaaldrich/product/images/296/089/259ad19e-25e1-4604-9077-8d4dbea518b6/640/259ad19e-25e1-4604-9077-8d4dbea518b6.jpg)
fonte biológica
rabbit
conjugado
agarose conjugate
forma do anticorpo
affinity isolated antibody
tipo de produto de anticorpo
primary antibodies
clone
polyclonal
reatividade de espécies
human
classe(s) química(is) do analito
proteins (c-Myc)
técnica(s)
affinity chromatography: suitable
immunoprecipitation (IP): suitable
capacidade
≥10 nmol/mL binding capacity (c-Myc tagged fusion protein)
≥7 nmol/mL elution capacity (c-Myc tagged fusion protein)
nº de adesão UniProt
temperatura de armazenamento
2-8°C
Informações sobre genes
human ... MYC(4609)
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Descrição geral
The human c-Myc proto-oncogene belongs to MYC oncogene family and is the human cellular homolog of the avian v-Myc gene found in several leukemogenic retroviruses. c-Myc gene is localized on human chromosome 8q24.21. The two major domains of include the N-terminal box regions and the C-terminal basic-region with helix-loop-helix/leucine-zipper motif.
Especificidade
Anti-c-Myc recognizes an epitope located on c-Myc tagged fusion proteins.
Imunogênio
synthetic peptide of the human p62c-Myc protein.
Aplicação
Anti-c-Myc Agarose Affinity Gel antibody produced in rabbit has been used in:
- chromatin immunoprecipitation (ChIP)
- co-immunoprecipitation
- western blotting
- immunofluorescence
- immunoprecipitation
Ações bioquímicas/fisiológicas
c-Myc proto-oncogene increased expression is observed in a variety of human tumors. Amplification of Myc gene locus is observed in angiosarcomas and translocation is implicated in Burkitt′s lymphoma. c-Myc is a master regulator and targets a wide variety of metabolic events. An epitope located within amino acid residues 410-419 (EQKLISEEDL) of human c-Myc has been widely used as a tag in many expression vectors, enabling the expression of proteins as c-Myc tagged fusion proteins. Anti-c-Myc agarose is useful in the purification of expressed c-Myc tagged fusion proteins in bacterial lysates or transfected cells.
forma física
Suspension of beaded agarose (1:1 v/v) in 0.01 M phosphate buffered saline containing 15 mM sodium azide.
Armazenamento e estabilidade
For continuous use and extended storage, store at 2 °C to 8 °C. Do not freeze.
Exoneração de responsabilidade
Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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produto relacionado
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
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