D0710000

Dexamethasone acetate

European Pharmacopoeia (EP) Reference Standard

• Sinônimo(s): Dexamethasone 21-acetate, 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione-21-acetate, 9α-Fluoro-16α-methylprednisolone-21-acetate, Prednisolone F acetate
• Fórmula empírica (Notação de Hill): C₂₄H₃₁FO₆
• Número CAS: 1177-87-3
• Peso molecular: 434.50
• Beilstein: 2342608
• Número MDL: MFCD00027407
• Código UNSPSC: 41116107
• ID de substância PubChem: 329798629
• NACRES: NA.24

Propriedades

• fonte biológica: synthetic
• grau: pharmaceutical primary standard
• Agency: EP
• família API: dexamethasone
• embalagem: pkg of 150 mg
• fabricante/nome comercial: EDQM
• condição de armazenamento: protect from light
• cor: white
• solubilidade: water: <0.1 g/L
• aplicação(ões): pharmaceutical (small molecule)
• Formato: neat
• Condições de expedição: ambient
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1
• chave InChI: AKUJBENLRBOFTD-RPRRAYFGSA-N
• Informações sobre genes: human ... NR3C1(2908)

Descrição

Descrição geral

Dexamethasone acetate (Decadron-LA) belongs to the class of long-acting glucocorticoids,[1] commonly used as a pharmaceutical ingredient in creams,[2] ointments,[3] microemulsions, lotions, aerosols, etc.[4]
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Dexamethasone acetate is used as an EP reference standard to quantify the analyte in pharmaceutical formulations using chromatography ttechniques.[5][2][3]

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Informações de segurança

• Pictogramas: GHS08
• Palavra indicadora: Danger
• Frases de perigo: H360FD
• Declarações de precaução: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Classificações de perigo: Repr. 1B
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 3