410225

Glicina

≥98.5%, for peptide synthesis

• Sinônimo(s): Glicocol, Ácido aminoacético, Ácido aminoetanoico
• Fórmula linear: NH₂CH₂COOH
• Número CAS: 56-40-6
• Peso molecular: 75.07
• Beilstein: 635782
• Número CE: 200-272-2
• Número MDL: MFCD00008131
• Código UNSPSC: 12352209
• eCl@ss: 32160406
• ID de substância PubChem: 24865701
• NACRES: NA.21

Propriedades

• product name: Glicina, ACS reagent, ≥98.5%
• grau: ACS reagent
• Nível de qualidade: 200
• Ensaio: ≥98.5%
• forma: powder, crystals or granules
• Impurezas: H₂SO₄, passes test (darkened); Hydrolyzable subsances, passes test
• resíduo de ignição: ≤0.1%
• cor: white
• pKa (25 °C): (1) 2.35, (2) 9.60; 2.35
• pf: 240 °C (dec.) (lit.)
• traços de ânion: chloride (Cl^-): ≤0.005%; sulfate (SO₄^2-): ≤0.005%
• traços de cátion: NH₄⁺: ≤0.005%; heavy metals: ≤0.002% (by ICP)
• aplicação(ões): peptide synthesis
• cadeia de caracteres SMILES: NCC(O)=O
• InChI: 1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
• chave InChI: DHMQDGOQFOQNFH-UHFFFAOYSA-N
• Informações sobre genes: rat ... Grin2a(24409)

Descrição

Descrição geral

Glycine is the simplest amino acid building block.

Aplicação

Glycine has been used in whole-cell patch clamp recording to measure inward NMDA (N-methyl-D-aspartate) currents. It has also been used as a model organic system in crystallography to demonstrate a novel acoustic nebulization platform.

Ações bioquímicas/fisiológicas

Glycine is a non-essential amino acid. Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors. Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.

Neurotransmissor inibitório na coluna vertebral, regulador alostérico dos receptores de NMDA.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)