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31493

Sigma-Aldrich

Salicilato de sódio

puriss. p.a., reag. Ph. Eur., 99.5-101.0% (calc. to the dried substance)

Sinônimo(s):

2-Hidroxibenzoato de sódio, Ácido 2-hidroxibenzoico, Ácido salicílico

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About This Item

Fórmula linear:
HOC6H4COONa
Número CAS:
Peso molecular:
160.10
Beilstein:
3732792
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de substância PubChem:
NACRES:
NA.21

Agency

USP/NF
reag. Ph. Eur.

Nível de qualidade

grau

puriss. p.a.

Ensaio

99.5-101.0% (calc. to the dried substance)

Impurezas

acidic reac. impurities, complies
sulfite or thiosulfate, complies
≤0.001% heavy metals (as Pb)

perda

≤0.3% loss on drying, 105 °C

pf

>300 °C (lit.)

traços de ânion

chloride (Cl-): ≤20 mg/kg
sulfate (SO42-): ≤500 mg/kg

traços de cátion

Fe: ≤10 mg/kg

adequação

in accordance for appearance of solution

cadeia de caracteres SMILES

[Na+].Oc1ccccc1C([O-])=O

InChI

1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1

chave InChI

ABBQHOQBGMUPJH-UHFFFAOYSA-M

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Descrição geral

Sodium salicylate can be prepared from the reaction of salicylic acid and ammonia. It exhibits fluorescence at higher concentrations and effectively absorbs β-particles. Due to these properties, it has been employed as fluor for the radioactivity detection in various gels.

Aplicação

Sodium salicylate may be used as phenolic reagent in salicylate method for the determination of ammonia. It may be employed as a hydrotropic agent to study the release of anticancer drug camptothecin (CPT) from the mixed micelles [composed of Pluronic P105 (P105) and D-α-tocopheryl polyethylene glycol 1000 succinate (TPGS)].

Pictogramas

Health hazardExclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Acute Tox. 4 Oral - Eye Irrit. 2 - Repr. 2

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 1

Ponto de fulgor (°F)

208.9 °F - Pensky-Martens closed cup

Ponto de fulgor (°C)

98.3 °C - Pensky-Martens closed cup

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves


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Yan Gao et al.
Colloids and surfaces. B, Biointerfaces, 64(2), 194-199 (2008-03-08)
To increase the solubility and cytotoxicity of poorly soluble anticancer drug camptothecin (CPT), mixed micelles made of Pluronic P105 (P105) and d-alpha-tocopheryl polyethylene glycol 1,000 succinate (TPGS) were prepared. The interaction of Pluronic and TPGS was studied and critical micelle
Ammonia determination based on indophenol formation with sodium salicylate.
Verdouw H, et al.
Water Research, 12(6), 399-402 (1978)
Fluorographic detection of radioactivity in polyacrylamide gels with the water-soluble fluor, sodium salicylate.
J P Chamberlain
Analytical biochemistry, 98(1), 132-135 (1979-09-15)
Kui Wang et al.
Journal of medicinal chemistry, 52(20), 6402-6412 (2009-10-16)
Viologens are showing an increasing number of scientific and technical applications in addition to their use as herbicides. However, their high toxicity poses considerable risks to human health, society, and the environment. In this context, we propose a new therapeutic
Rainer Amann et al.
European journal of pharmacology, 447(1), 1-9 (2002-07-11)
Aspirin (acetylsalicylic acid) is one of the most widely used drugs worldwide. It acetylates cyclooxygenases thereby irreversibly blocking the conversion of arachidonic acid to prostanoids. Biotransformation of aspirin yields salicylate, a compound that possesses similar anti-inflammatory potency as aspirin but

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