131164

Indigo carmine

certified by the Biological Stain Commission, Dye content 85 %

• Sinônimo(s): Acid Blue 74, Indigo-5,5′-disulfonic acid disodium salt, Indigocarmine
• Fórmula empírica (Notação de Hill): C₁₆H₈N₂Na₂O₈S₂
• Número CAS: 860-22-0
• Peso molecular: 466.35
• Número do índice de cores: 73015
• Beilstein: 4103904
• Número CE: 212-728-8
• Número MDL: MFCD00005723
• Código UNSPSC: 12171500
• ID de substância PubChem: 24847997
• NACRES: NA.47

Propriedades

• grau: certified by the Biological Stain Commission
• Nível de qualidade: 200
• Ensaio: >85.0% (HPLC)
• forma: solid
• composição: Dye content, 85%
• cor: dark blue to very dark blue
• pH: 3.87 (30 °C, 7.14 g/L)
• pf: ≥340 °C
• densidade: 0.71 g/cm³ at 29 °C
• λmax: 608 nm
• εmax: 20,000 at 250-256 nm in water at 0.01 g/L; 29500 at 284-290 nm in water at 0.01 g/L
• aplicação(ões): diagnostic assay manufacturing; hematology; histology
• temperatura de armazenamento: room temp
• cadeia de caracteres SMILES: [Na+].[Na+].[O-]S(=O)(=O)c1ccc2NC(\C(=O)c2c1)=C3\Nc4ccc(cc4C3=O)S([O-])(=O)=O
• InChI: 1S/C16H10N2O8S2.2Na/c19-15-9-5-7(27(21,22)23)1-3-11(9)17-13(15)14-16(20)10-6-8(28(24,25)26)2-4-12(10)18-14;;/h1-6,17-18H,(H,21,22,23)(H,24,25,26);;/q;2*+1/p-2/b14-13+;;
• chave InChI: KHLVKKOJDHCJMG-QDBORUFSSA-L

Descrição

Aplicação

Indigo carmine has been used to investigate its effects on ozone production by neutrophils.

Ações bioquímicas/fisiológicas

Indigo Carmine (IC), commonly known as acid blue 74 or food blue 1 or FD and C blue 2 is a blue synthetic dye. It is used as a redox indicator in analytical chemistry and as a microscopic stain in biology. IC is also employed as a photometric detector. IC is a highly toxic indigoid dye and is associated with various health hazards such as irritation to the gastrointestinal tract leading to nausea, vomiting, and diarrhea and irritation in the respiratory tract leading to coughing and shortness of breath. IC exposure might also cause skin and eye irritations to humans. IC dye spray is used for the diagnosis of dysplasia in ulcerative colitis and is considered to be a simple, feasible, and safe method.

Adequação

Used as a collagen stain and in procedures using red nuclear stains.

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H317
• Declarações de precaução: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Classificações de perigo: Skin Sens. 1
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves