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B79803

Sigma-Aldrich

3-Bromopropylamine hydrobromide

3-Bromopropylamine hydrobromide

98%

Sinônimo(s):

3-Aminopropyl bromide hydrobromide

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About This Item

Fórmula linear:
BrCH2CH2CH2NH2 · HBr
Número CAS:
5003-71-4
Peso molecular:
218.92
Beilstein:
3906418
Número CE:
225-675-0
Número MDL:
MFCD00012912
Código UNSPSC:
12352100
ID de substância PubChem:
24892034
NACRES:
NA.22
Preço e disponibilidade não estão disponíveis no momento.

Nível de qualidade

200

Ensaio

98%

Formulário

crystals

pf

171-172 °C (lit.)

cadeia de caracteres SMILES

Br.NCCCBr

InChI

1S/C3H8BrN.BrH/c4-2-1-3-5;/h1-3,5H2;1H

chave InChI

PQIYSSSTRHVOBW-UHFFFAOYSA-N

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Aplicação

3-Bromopropylamine hydrobromide is commonly used as a reagent to introduce propylamine group to the molecular skeleton.[1][2][3] Some of the other reported applications include:
  • Synthesis of photochemically and thermally reactive azobenzene rotaxane[1] and indolocarbazole-containing [2]rotaxane.[4]
  • Synthesis of indenoisoquinoline based active topoisomerase I inhibitors as anticancer agents.[2][5]

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

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Certificados de análise (COA)

Lot/Batch Number
0000346578
0000346578
MKCW4913
0000243976
MKCT7792

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Nature, 559(7714), 410-414 (2018-07-12)
Mutations in the E3 ubiquitin ligase parkin (PARK2, also known as PRKN) and the protein kinase PINK1 (also known as PARK6) are linked to autosomal-recessive juvenile parkinsonism (AR-JP)1,2; at the cellular level, these mutations cause defects in mitophagy, the process
A multi-mode-driven molecular shuttle: photochemically and thermally reactive azobenzene rotaxanes.
Murakami H, et al.
Journal of the American Chemical Society, 127(45), 15891-15899 (2005)
Antagonist analogue of 6-[3 `-(1-adamantyl)-4 `-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN) family of apoptosis inducers that effectively blocks AHPN-induced apoptosis but not cell-cycle arrest.
Dawson M I, et al.
Journal of Medicinal Chemistry, 47(14), 3518-3536 (2004)
Maya Juenet et al.
Biomaterials, 156, 204-216 (2017-12-08)
Injection of recombinant tissue plasminogen activator (rt-PA) is the standard drug treatment for thrombolysis. However, rt-PA shows risk of hemorrhages and limited efficiency even at high doses. Polysaccharide-poly(isobutylcyanoacrylate) nanoparticles functionalized with fucoidan and loaded with rt-PA were designed to accumulate
Optimization of the indenone ring of indenoisoquinoline topoisomerase I inhibitors.
Morrell A, et al.
Journal of Medicinal Chemistry, 50(18), 4388-4404 (2007)
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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  1. London, UK
    • Reviews 3
    • Votes 0
    5 out of 5 stars.

    Best Customer service

    It met our requirement and shipping was on time. The purchasing process was easy as well.

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