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791628

Sigma-Aldrich

Trimethylamine-d9 N-Oxide

98 atom % D, 98% (CP)

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About This Item

Fórmula empírica (Notação de Hill):
C3D9NO
Número CAS:
Peso molecular:
84.17
Código UNSPSC:
12352116
ID de substância PubChem:

Note: This product can be packaged on demand. For information on pricing, availability and packaging of custom sizes, please contact Stable Isotopes Customer Service

pureza isotópica

98 atom % D

Ensaio

98% (CP)

Formulário

solid

técnica(s)

bio NMR: suitable

alteração de massa

M+9

cadeia de caracteres SMILES

[O-][N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]

InChI

1S/C3H9NO/c1-4(2,3)5/h1-3H3/i1D3,2D3,3D3

chave InChI

UYPYRKYUKCHHIB-GQALSZNTSA-N

Categorias relacionadas

Descrição geral

Trimethylamine-d9 is isotopically enriched molecule.

Aplicação

Trimethylamine-d9 N-oxide is used in the stability of hydrogen bonding between peptide, water with trimethylamine N-oxide.It is also used as an internal standard for the quantification of trimethylamine N-oxide by GC- or LC-MS.

Embalagem

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Makiko Shimizu et al.
The Journal of toxicological sciences, 43(6), 387-393 (2018-06-08)
Medicinal carnitine-derived and dietary-derived malodorous trimethylamine and its non-malodorous metabolite trimethylamine N-oxide were historically regarded as nontoxic. Clinical and toxicological interest has recently arisen because of their potential association with atherosclerosis. We previously reported a human physiologically based pharmacokinetic (PBPK)
Tsung-Jen Lin et al.
Nutrition (Burbank, Los Angeles County, Calif.), 66, 29-37 (2019-06-16)
A plant-based diet has been associated with a reduced risk of cardiovascular (CV) diseases. This study aimed to determine the levels and correlations of CV-related biomarkers and the beneficial role of dietary habits. A total of 63 healthy vegetarians (n = 32)
Zeneng Wang et al.
Analytical biochemistry, 455, 35-40 (2014-04-08)
Trimethylamine-N-oxide (TMAO) levels in blood predict future risk for major adverse cardiac events including myocardial infarction, stroke, and death. Thus, the rapid determination of circulating TMAO concentration is of clinical interest. Here we report a method to measure TMAO in
Xiang Zhou et al.
ESC heart failure, 7(1), 188-193 (2020-01-22)
Accumulating evidence has demonstrated that intestinal microbiota-dependent trimethylamine N-oxide (TMAO) is involved in the pathogenesis of various cardiovascular diseases. The present study was designed to investigate the prognostic value of TMAO in patients with chronic heart failure (CHF) after myocardial
Filip Meersman et al.
Biophysical journal, 97(9), 2559-2566 (2009-11-04)
Trimethylamine N-oxide (TMAO) is a naturally occurring osmolyte that stabilizes proteins, induces folding, and counteracts the denaturing effects of urea, pressure, and ice. To establish the mechanism behind these effects, isotopic substitution neutron-scattering measurements were performed on aqueous solutions of

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