429066

(3-Bromopropoxy)-tert-butyldimethylsilane

97%

• Sinônimo(s): (3-Bromopropoxy)(1,1-dimethylethyl)dimethylsilane, 1-((tert-Butyldimethylsilyl)oxy)-3-bromopropane, 1-Bromo-3-(tert-butyldimethylsiloxy)propane, 1-Bromo-3-[(tert-butyldimethylsilanyl)oxy]propane, 1-Bromo-3-[(tert-butyldimethylsilyl)oxy]propane, 3-((tert-Butyldimethylsilyl)oxy)-1-bromopropane
• Fórmula linear: Br(CH₂)₃OSi(CH₃)₂C(CH₃)₃
• Número CAS: 89031-84-5
• Peso molecular: 253.25
• Número MDL: MFCD00216589
• Código UNSPSC: 12352100
• ID de substância PubChem: 24866833
• NACRES: NA.22

Propriedades

• Ensaio: 97%
• Formulário: liquid
• contém: sodium carbonate as stabilizer
• índice de refração: n20/D 1.451 (lit.)
• p.e.: 182 °C (lit.)
• densidade: 1.093 g/mL at 25 °C (lit.)
• grupo funcional: bromo
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: CC(C)(C)[Si](C)(C)OCCCBr
• InChI: 1S/C9H21BrOSi/c1-9(2,3)12(4,5)11-8-6-7-10/h6-8H2,1-5H3
• chave InChI: QGMROEZDWJTIDW-UHFFFAOYSA-N

Descrição

Descrição geral

(3-Bromopropoxy)-tert-butyldimethylsilane is a bromo silyl ether.

Aplicação

(3-Bromopropoxy)-tert-butyldimethylsilane may be used to introduce propanol functionality to many pharmaceuticals.[1][2][3][4]
It may be used as an alkylating agent in the synthesis of the following:

• N-[2-[N-[3-(tert-butyldimethylsilyloxy)propyl]-N-ethylamino]ethyl]phthalimide[5]
• O-(3-tert-butyldimethylsilyloxypropyl)-N-(tert-butoxycarbonyl)-L-tyrosine methyl ester[6]
• tert-butyldimethyl-[3-(3-methyl-2-nitrophenoxy)propoxy]silane[7]

Informações de segurança

• Pictogramas: GHS07
• Palavra indicadora: Warning
• Frases de perigo: H315,H319,H335
• Declarações de precaução: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): 185.0 °F - closed cup
• Ponto de fulgor (°C): 85 °C - closed cup