SML0325

Retigabin

≥98% (HPLC)

• Synonym(e): N-(2-Amino-4-(4-fluorbenzylamino)-phenyl)-carbaminsäure-ethylester, D-23129, Ezogabin
• Empirische Formel (Hill-System): C₁₆H₁₈FN₃O₂
• CAS-Nummer: 150812-12-7
• Molekulargewicht: 303.33
• UNSPSC Code: 12352200
• NACRES: NA.77
• PubChem Substance ID: 329825330
• MDL number: MFCD04307735
• Beilstein/REAXYS Number: 8072099
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• drug control: USDEA Schedule V
• color: white to light brown
• solubility: DMSO: >15 mg/mL
• storage temp.: room temp
• SMILES string: FC1=CC=C(CNC2=CC(N)=C(NC(OCC)=O)C=C2)C=C1
• InChI: 1S/C16H18FN3O2/c1-2-22-16(21)20-15-8-7-13(9-14(15)18)19-10-11-3-5-12(17)6-4-11/h3-9,19H,2,10,18H2,1H3,(H,20,21)
• InChI key: PCOBBVZJEWWZFR-UHFFFAOYSA-N
• Gene Information: human ... KCNQ1(3784), KCNQ2(3785), KCNQ3(3786), KCNQ4(9132), KCNQ5(56479)

Beschreibung

Biochem/physiol Actions

Retigabine (Ezogabine) is a Kv7.2-7.5 (KCNQ2-5) neuronal potassium channel opener witrh anticonvulsant activity.

Retigabine is a Kv7.2-7.5 potassium channel activator; anticonvulsant.

Sicherheitshinweise

• pictograms: GHS06,GHS09
• signalword: Danger
• hcodes: H301 + H331,H410
• pcodes: P261 - P264 - P271 - P273 - P301 + P310 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable