PZ0006

Exemestan

≥98% (HPLC)

• Synonym(e): 6-Methylenandrosta-1,4-dien-3,17-dion
• Empirische Formel (Hill-System): C₂₀H₂₄O₂
• CAS-Nummer: 107868-30-4
• Molekulargewicht: 296.40
• MDL-Nummer: MFCD00866994
• UNSPSC-Code: 51111800
• PubChem Substanz-ID: 329823675
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Optische Aktivität: [α]/D +250 to +300°, c = 1 in methanol
• Farbe: white to off-white
• Löslichkeit: DMSO: ≥20 mg/mL
• Lagertemp.: 2-8°C
• SMILES String: C[C@]12CC[C@H]3[C@@H](CC(=C)C4=CC(=O)C=C[C@]34C)[C@@H]1CCC2=O
• InChI: 1S/C20H24O2/c1-12-10-14-15-4-5-18(22)20(15,3)9-7-16(14)19(2)8-6-13(21)11-17(12)19/h6,8,11,14-16H,1,4-5,7,9-10H2,2-3H3/t14-,15-,16-,19+,20-/m0/s1
• InChIKey: BFYIZQONLCFLEV-DAELLWKTSA-N
• Angaben zum Gen: human ... CYP19A1(1588)

Beschreibung

Biochem./physiol. Wirkung

Exemestane is a steroidal antiestrogen and irreversible aromatase inhibitor. Exemestane acts as a false substrate for the aromatase enzyme. Exemestane also prevents the conversion of androgens to estrogens and is used to treat estrogen-dependent breast cancer.

Exemestane is a steroidal antiestrogen; aromatase inhibitor.

Leistungsmerkmale und Vorteile

This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sicherheitshinweise

• Piktogramme: GHS08,GHS09
• Signalwort: Danger
• H-Sätze: H360,H411
• P-Sätze: P202 - P273 - P280 - P308 + P313 - P391 - P405
• Gefahreneinstufungen: Aquatic Chronic 2 - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable