14-720-M

FAK Protein, active, 10 µg

Active, N-terminal 6His-tagged, recombinant, human FAK, amino acids 411-686, for use in Kinase Assays.

• UNSPSC-Code: 12352202
• eCl@ss: 32160405
• NACRES: NA.32

Eigenschaften

• Biologische Quelle: human
• Qualitätsniveau: 100
• Rekombinant: expressed in baculovirus infected Sf21 cells
• Produktlinie: Upstate^®
• Spezifische Aktivität: (For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.)
• Mol-Gew.: M_w 35.5 kDa
• Aufgereinigt durch: (Ni²⁺/NTA-agarose)
• Speziesreaktivität: human
• Hersteller/Markenname: Upstate^®
• Methode(n): activity assay: suitable (kinase)
• Hinterlegungsnummer: (FUNCTION: SwissProt: Q05397 # Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. ); NM_005607.3
• NCBI-Hinterlegungsnummer: NM_005607.3; NM_153831.2
• UniProt-Hinterlegungsnummer: Q05397
• Relevante Krankheit(en): obesity; metabolic disorders
• Angaben zum Gen: human ... PTK2(5747)

Beschreibung

Allgemeine Beschreibung

N-terminal 6His-tagged, recombinant, human FAK, amino acids 411-686

Biochem./physiol. Wirkung

Protein Target: FAK

Verpackung

Also available in 10 μg size and in bulk

Qualität

routinely evaluated by phosphorylation of 100μM substrate peptide (EEEEYEEEEEEYYIIEEEEEEYEEEEEEYYEEEEEEKKK)

Zielbeschreibung

FAK

Sonstige Hinweise

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Rechtliche Hinweise

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H317
• P-Sätze: P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
• Gefahreneinstufungen: Skin Sens. 1
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°C): Not applicable