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Merck

182028

Sigma-Aldrich

Poly(ethylenoxid)

average MV 600,000 (nominal), powder, hydroxyl, BHT as inhibitor

Synonym(e):

PEO

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About This Item

Lineare Formel:
(-CH2CH2O-)n
CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352104
PubChem Substanz-ID:
NACRES:
NA.23
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Produktbezeichnung

Poly(ethylenoxid), average Mv 600,000 (nominal), powder

Form

powder

Qualitätsniveau

Mol-Gew.

average Mv 600,000 (nominal)

Enthält

200-500 ppm BHT as inhibitor

Viskosität

4,500-8,800 cP, 5 % in H2O(25 °C, Brookfield)(lit.)

Übergangstemp.

Tm 65 °C

Ω-Ende

hydroxyl

α-Ende

hydroxyl

Anwendung(en)

battery manufacturing

SMILES String

[H]OCCO

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChIKey

LYCAIKOWRPUZTN-UHFFFAOYSA-N

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Allgemeine Beschreibung

Poly(ethylenoxid)(PEO) ist ein nichtionisches wasserlösliches Polymer mit hoher Molekülmasse. Es bildet einGel bei der Hydrierung und weist eine gute Quellkapazität auf. PEO-Polymere sind nichttoxischund werden verbreitet in Arzneimittelabgabesystemen verwendet, um die Arzneimittellöslichkeit zu verbessern.

Anwendung

Poly(ethylenoxid) kann zum Herstellen von Folgendem verwendet werden:
  • Bioabsorbierbare und injizierbare Hydrogele für die verzögerte Arzneimittelfreisetzung.
  • PEO/Graphenoxid-Verbundmaterial-Elektrolytmembran für Brennstoffzellen.
  • Poly(ethylenoxid)-b-poly(ε-caprolacton)(PEO-b-PCL)-Diblockcopolymer. Losartankalium-eingekapseltes (PEO-b-PCL) Copolymer kann als Arzneimittelträger verwendet werden.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Jun Li et al.
Journal of biomedical materials research. Part A, 65(2), 196-202 (2003-05-08)
Polymeric hydrogels long have attracted interest for biomaterials applications because of their generally favorable biocompatibility. High in water content, they are particularly attractive for delivery of delicate bioactive agents, such as proteins. However, because they require covalent crosslinking for gelation
Angeliki Chroni et al.
Nanomaterials (Basel, Switzerland), 10(9) (2020-09-24)
We report on the preparation of drug nanocarriers by encapsulating losartan potassium (LSR) into amphiphilic block copolymer micelles, utilizing the biocompatible/biodegradable poly(ethylene oxide)-b-poly(ε-caprolactone) (PEO-b-PCL) diblock copolymer. The PEO-b-PCL micelles and LSR-loaded PEO-b-PCL nanocarriers were prepared by organic solvent evaporation method
I L Konorova et al.
Patologicheskaia fiziologiia i eksperimental'naia terapiia, (4)(4), 7-9 (1991-07-01)
The search for antiaggregatory compounds is undertaken, as a rule, under in vitro conditions which do not reflect the dynamics of the real process. The present work deals with study of the peculiarities of the development of the collagen induced
P I Polimeni et al.
Journal of cardiovascular pharmacology, 14(3), 374-380 (1989-09-01)
The acute hemodynamic effects of an intravenously (i.v.) injected poly(ethylene oxide), Polyox WSR N-60K (dose 50 mg/kg), were studied in the open-chest rat anesthetized with sodium pentobarbital. The injectate is one of four drag-reducing polymers known to augment in vitro
D D Smyth et al.
Cardiovascular drugs and therapy, 4(1), 297-300 (1990-02-01)
Previous studies have demonstrated that Separan AP-30, a drag-reducing polymer, significantly decreased the formation of atherosclerotic plaques in rabbits fed a high-cholesterol diet. Furthermore, Separan AP-273, a polymer similar to but longer than Separan AP-30, markedly increased cardiac output in

Artikel

Electrospinning technique applications discussed, emphasizing control of nanofibers and assembly into 3D architectures.

Progress in biotechnology fields such as tissue engineering and drug delivery is accompanied by an increasing demand for diverse functional biomaterials. One class of biomaterials that has been the subject of intense research interest is hydrogels, because they closely mimic the natural environment of cells, both chemically and physically and therefore can be used as support to grow cells. This article specifically discusses poly(ethylene glycol) (PEG) hydrogels, which are good for biological applications because they do not generally elicit an immune response. PEGs offer a readily available, easy to modify polymer for widespread use in hydrogel fabrication, including 2D and 3D scaffold for tissue culture. The degradable linkages also enable a variety of applications for release of therapeutic agents.

Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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