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TRPV1

transient receptor potential cation channel, subfamily V, member 1

Synonyme:
VR1
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(7442) Summary: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(193034) transient receptor potential cation channel, subfamily V, member 1
  • Rat(83810) transient receptor potential cation channel, subfamily V, member 1
  • domestic cat(101093406) transient receptor potential cation channel, subfamily V, member 1
  • chicken(395259) transient receptor potential cation channel, subfamily V, member 1
  • naked mole-rat(101720480) transient receptor potential cation channel, subfamily V, member 1
  • Domestic Rabbit(100008926) transient receptor potential cation channel, subfamily V, member 1
  • domestic cat(100303454) transient receptor potential cation channel, subfamily V, member 1
  • Zebrafish(561195) transient receptor potential cation channel, subfamily V, member 1
  • cow(539074) transient receptor potential cation channel, subfamily V, member 1
  • domestic guinea pig(100135466) transient receptor potential cation channel, subfamily V, member 1
  • Horse(100034158) transient receptor potential cation channel, subfamily V, member 1
  • sheep(101110158) transient receptor potential cation channel, subfamily V, member 1
  • dog(445457) transient receptor potential cation channel, subfamily V, member 1

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
Dihydrocapsaicin, from Capsicum sp., ≥85%,
Spezies
rat, human
Pelargonsäure-vanillylamid, ≥97%, powder,
Spezies
rat
N-Oleoylethanolamine, ~98% (TLC),
Spezies
human, mouse, rat

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
SB-366791, ≥98% (HPLC), powder,
Spezies
human
6-Iodonordihydrocapsaicin, ≥98% (HPLC), solid,
Spezies
human
Capsazepine, ≥98% (HPLC), solid,
Spezies
human, rat
Capsaicin, ≥95%, from Capsicum sp.,
Spezies
rat, human
Capsaicin, natural,
Spezies
rat, human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Capsaicin-Rezeptor-Antikörper, C-Terminus, serum, Chemicon®,
Speziesreaktivität
rat
Anwendung
immunohistochemistry
Anti-TRPV1 antibody produced in rabbit, ,
Speziesreaktivität
human, mouse, rat
Anwendung
immunofluorescence
western blot
Anti-TRPV1 antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
ELISA
western blot
Monoclonal Anti-TRPV1 antibody produced in mouse, clone 1F5, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
western blot
Anti-TRPV1 Antibody, clone 1N19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human, monkey, mouse
Anwendung
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Olvanil, powder,
Spezies
human
Capsaicin, ≥95%, from Capsicum sp.,
Spezies
rat, human
4-Acetamidophenol, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Acetaminophen, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
4-Acetamidophenol, BioXtra, ≥99.0%,
Spezies
human

Small Molecule - Mixed Agonist/Antagonist

Produktnummer
Beschreibung
Spezies
Pelargonsäure-vanillylamid, ≥97%, powder,
Spezies
rat
Capsazepine, ≥98% (HPLC), solid,
Spezies
human, rat

Small Molecule - Opener

Produktnummer
Beschreibung
Spezies
Capsaicin, analytical standard,
Spezies
human
Capsaicin, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Capsaicin, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Capsaicin, phyproof® Reference Substance,
Spezies
human
Capsaicin, European Pharmacopoeia (EP) Reference Standard,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human TRPV1,
Spezies
human
MISSION® esiRNA, targeting mouse Trpv1,
Spezies
mouse