Direkt zum Inhalt
Merck

HTR2B

5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

Synonyme:
5-HT(2B), 5-HT2B
Spezies:
Human HTR2B (3357), Mouse Htr2b (15559), Rat Htr2b (29581), chicken HTR2B (395581), Zebrafish htr2b (751784), dog HTR2B (403881), cow HTR2B (407135), Horse HTR2B (100057052), domestic cat HTR2B (101095762), Domestic Rabbit HTR2B (100343392) ...Mehr
UniProtKB-ID:
P41595, B2R9D5, Q53TI1, Q62221, Q6P523
Gen-ID:
  • Human(3357) Summary: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. [provided by RefSeq, Oct 2011]
  • Mouse(15559) 5-hydroxytryptamine (serotonin) receptor 2B
  • Rat(29581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • chicken(395581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Zebrafish(751784) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • dog(403881) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • cow(407135) 5-hydroxytryptamine (serotonin) receptor 2B
  • Horse(100057052) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic cat(101095762) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Domestic Rabbit(100343392) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • sheep(101106827) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • naked mole-rat(101699201) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic guinea pig(100135546) 5-hydroxytryptamine (serotonin) receptor 2B

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
B175
BW 723C86, ≥98% (HPLC),
Spezies
human
1430000
Methylergonovinmaleat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Y0000776
Methylergometrinmaleat, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
Y0000777
Methylergometrin für die Systemeignung, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
N7261
Nortriptylin -hydrochlorid, ≥98% (HPLC), powder,
Spezies
human

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
D9190
DCEBIO, ≥98% (HPLC), solid,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
1430000
Methylergonovinmaleat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Y0000776
Methylergometrinmaleat, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
Y0000777
Methylergometrin für die Systemeignung, European Pharmacopoeia (EP) Reference Standard,
Spezies
human
S006
Ketanserin -tartrat, ≥97%, solid,
Spezies
human
C4542
Cyclobenzaprin -hydrochlorid, ,
Spezies
human

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
HPA012867
Anti-HTR2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry
SAB4501476
Anti-HTR2B antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence
western blot
HPA063658
Anti-HTR2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence
SAB4501475
Anti-5-HT-2B antibody produced in rabbit, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
ELISA
immunofluorescence
immunohistochemistry
western blot
AMAB91972
Monoclonal Anti-Htr2B Antibody Produced In Mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL14576, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
western blot

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
M2525
Mianserin -hydrochlorid, ,
Spezies
human
T3146
Trimipramin -maleat (Salz), ≥98% (TLC), powder,
Spezies
human
Z101
Zimelidin -dihydrochlorid, solid,
Spezies
human

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
N7261
Nortriptylin -hydrochlorid, ≥98% (HPLC), powder,
Spezies
human
A129
Amoxapin, ,
Spezies
human
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Spezies
human
F1678
R-(−)-Fluoxetin -hydrochlorid, >98% (HPLC), solid,
Spezies
human
F132
Fluoxetin -hydrochlorid, solid,
Spezies
human

Small Molecule - Ligand

Produktnummer
Beschreibung
Spezies
M1514
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Spezies
human

Small Molecule - Metabolite

Produktnummer
Beschreibung
Spezies
H8876
5-Hydroxyindol-3-Essigsäure, ≥98% (HPLC), crystalline,
Spezies
human

Small Molecule - Mixed Agonist/Antagonist

Produktnummer
Beschreibung
Spezies
M8046
Mifepriston, ≥98%,
Spezies
human, mouse, rat
C6305
Clozapin, ,
Spezies
human, rat

Small Molecule - Precursor

Produktnummer
Beschreibung
Spezies
H9772
5-Hydroxy-L-Tryptophan, powder,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
EHU052881
MISSION® esiRNA, targeting human HTR2B,
Spezies
human