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Merck

GRIA3

glutamate receptor, ionotropic, AMPA 3

Synonyme:
GLUR-C, GLUR-K3, GLUR3, GLURC, GluA3, MRX94
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(2892) Summary: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties. [provided by RefSeq, Jul 2008]
  • Mouse(53623) glutamate receptor, ionotropic, AMPA3 (alpha 3)
  • Rat(29628) glutamate receptor, ionotropic, AMPA 3
  • chicken(396138) glutamate receptor, ionotropic, AMPA 3
  • sheep(443273) glutamate receptor, ionotropic, AMPA 3
  • cow(534626) glutamate receptor, ionotrophic, AMPA 3
  • dog(492110) glutamate receptor, ionotropic, AMPA 3
  • Horse(100055136) glutamate receptor, ionotropic, AMPA 3
  • naked mole-rat(101713289) glutamate receptor, ionotropic, AMPA 3
  • domestic cat(101089925) glutamate receptor, ionotropic, AMPA 3
  • Domestic Rabbit(100341980) glutamate receptor, ionotropic, AMPA 3

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Small Molecule - Agonist

Produktnummer
Beschreibung
Spezies
2,6-Difluoro-4-[2-(phenylsul­fonyl­amino)­ethyl­thio]­phenoxy­acet­amide, ≥98% (HPLC), solid,
Spezies
human
Cyclothiazid, ,
Spezies
human, rat
(±)-AMPA, solid,
Spezies
rat
(S)-AMPA, ≥98%,
Spezies
mouse, human, rat
(Aminomethyl)phosphonsäure, 99%,
Spezies
rat, human

Small Molecule - Allosteric Modulator

Produktnummer
Beschreibung
Spezies
CX546, ≥98% (HPLC), solid,
Spezies
human
Piracetam, ,
Spezies
human, rat
Cyclothiazid, ,
Spezies
human, rat
Topiramat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Topiramat, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human

Small Molecule - Antagonist

Produktnummer
Beschreibung
Spezies
GYKI 52466 hydrochloride, solid,
Spezies
human
Piracetam, ,
Spezies
human, rat
CNQX Dinatriumsalz Hydrat, ≥98% (HPLC), solid,
Spezies
human
NBQX Dinatriumsalz Hydrat, ≥98% (HPLC),
Spezies
human
(±)-AMPA, solid,
Spezies
rat

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-Glutamatrezeptor-3-Antikörper, Klon 3B3, clone 3B3, Chemicon®, from mouse,
Speziesreaktivität
human, monkey, mouse, rat
Anwendung
immunocytochemistry
immunohistochemistry

western blot
Anti-GRIA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Monoclonal Anti-GRIA3 antibody produced in mouse, clone 3D10, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
Anti-GRIA3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunohistochemistry

Small Molecule - Blocker

Produktnummer
Beschreibung
Spezies
Cyclothiazid, ,
Spezies
human, rat
Kynurensäure, ≥98%,
Spezies
rat, human
Topiramat, United States Pharmacopeia (USP) Reference Standard,
Spezies
human
Topiramat, Pharmaceutical Secondary Standard; Certified Reference Material,
Spezies
human
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
Spezies
human

Small Molecule - Mixed Agonist/Antagonist

Produktnummer
Beschreibung
Spezies
Cyclothiazid, ,
Spezies
human, rat
(±)-AMPA, solid,
Spezies
rat

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human GRIA3,
Spezies
human
MISSION® esiRNA, targeting mouse Gria3,
Spezies
mouse