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重要文件

S4751

Sigma-Aldrich

硬脂酸

Grade I, ≥98.5% (capillary GC)

同義詞:

1-十八碳烷酸, C18:0, NSC 25956, NSC 261168, 十八烷酸, 硬脂酸

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About This Item

線性公式:
CH3(CH2)16COOH
CAS號碼:
分子量::
284.48
Beilstein:
608585
EC號碼:
MDL號碼:
分類程式碼代碼:
12352106
PubChem物質ID:
NACRES:
NA.25
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等級

capillary GC grade

蒸汽壓力

1 mmHg ( 173.7 °C)

種類

Grade I

化驗

≥98.5% (capillary GC)

形狀

powder

bp

361 °C (lit.)

mp

67-72 °C (lit.)

溶解度

chloroform: 100 mg/mL, clear, colorless

密度

0.845 g/cm3

官能基

carboxylic acid

脂質類型

saturated FAs

運輸包裝

ambient

儲存溫度

2-8°C

SMILES 字串

CCCCCCCCCCCCCCCCCC(O)=O

InChI

1S/C18H36O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h2-17H2,1H3,(H,19,20)

InChI 密鑰

QIQXTHQIDYTFRH-UHFFFAOYSA-N

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一般說明

硬脂酸是一种C18饱和脂肪酸。[1]

應用

硬脂酸用于脂肪酸制备。[2][3][4]

生化/生理作用

β-硬脂酸氧化生成8个FADH2(黄素腺嘌呤二核苷酸)和NADH2(烟酰胺腺嘌呤二核苷酸)分子和9个乙酰辅酶A分子。[1]

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

nwg

閃點(°F)

392.0 °F - Cleveland open cup

閃點(°C)

200 °C - Cleveland open cup

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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分析證明 (COA)

Lot/Batch Number

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存取文件庫

Hypoxia potentiates palmitate-induced pro-inflammatory activation of primary human macrophages
Snodgrass Ryan G, et al.
The Journal of Biological Chemistry, 291(1), 413-424 (2016)
Sports Nutrition (1999)
Solid liquid phase diagrams of binary fatty acid mixtures?Palmitic/stearic with oleic/linoleic/linolenic acid mixture
Eckert Karl-Andreas, et al.
Thermochimica Acta, 630, 50-63 (2016)
Construction and comparison of solid liquid phase diagrams of binary sat-sat and unsat-unsat fatty acid mixtures comprising two of palmitic/stearic/oleic/linoleic/linolenic acid
Eckert KA, et al.
Journal of Environmental Research And Development, 10(4), 1-1 (2016)
Hua Ning et al.
Nutrients, 8(4), 227-227 (2016-04-23)
The detrimental role of hepatic lipotoxicity has been well-implicated in the pathogenesis of NAFLD. Previously, we reported that inhibiting autophagy aggravated saturated fatty acid (SFA)-induced hepatotoxicity. Insulin, a physiological inhibitor of autophagy, is commonly increased within NAFLD mainly caused by

文章

Supplement cell culture systems with fatty acids for biomanufacturing heterologous proteins like monoclonal antibodies.

Lipid Induced Insulin Resistance

脂肪组织中的胰岛素耐受性减少了循环游离脂肪酸的摄入,并增加了脂肪酶对储存甘油三酯的水解。了解与胰岛素耐受性相关的激素、细胞因子和脂肪因子。

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. Hello, what’s the difference between synthesis grade and grade 1? What kind of impurities are in both? Thank you.

    1 answer
    1. The Synthesis grade, product 8.00673, has been tested for suitability in synthesis applications. The Grade I, product S4751, is not tested for a specific application and is intended for general laboratory use. Unfortunately, the impurities are not identified in either of these products. Limited testing on impurities is performed on the Food Grade product, W303518.

      See the link below to review the specifications for this product option:
      https://www.sigmaaldrich.com/specification-sheets/234/856/W303518-BULK-K____ALDRICH__.pdf

      Helpful?

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