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Merck
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文件

O1257

Sigma-Aldrich

油酸-水溶性

powder, BioReagent, suitable for cell culture

同義詞:

油酸-环糊精复合物

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About This Item

MDL號碼:
MFCD00064242
分類程式碼代碼:
12352211
PubChem物質ID:
24897936
NACRES:
NA.75

生物源

synthetic (organic)

產品線

BioReagent

形狀

powder

成份

Oleic acid, ~30 mg/g (balance methyl-β-cyclodextrin)

技術

cell culture | mammalian: suitable

溶解度

H2O: 50 mg/mL, clear to slightly hazy

儲存溫度

−20°C

SMILES 字串

CCCCCCCC\C=C/CCCCCCCC(O)=O

InChI

1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-

InChI 密鑰

ZQPPMHVWECSIRJ-KTKRTIGZSA-N

基因資訊

human ... SOAT1(6646) , SOAT2(8435)

相關類別

應用

十八烯酸水溶液可用于：
  • 制备用于细胞处理的FFA（游离脂肪酸）混合物
  • 研究其对L6肌细胞中溶质载体家族2成员4 (SLC2A4)/GLUT4表达的影响，并用作潜在的转录调控因子
  • 制备脂肪培养基，用于诱导原代人肝细胞的体外脂肪变性

其他說明

甲基-β-环葡聚糖结合改善了油酸在培养基中的溶解度和运输。

相關產品

產品號碼
描述
訂價

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

分析證明 (COA)

輸入產品批次/批號來搜索 分析證明 (COA)。在產品’s標籤上找到批次和批號，寫有 ‘Lot’或‘Batch’.。

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Oleic and linoleic fatty acids downregulate Slc2a4/GLUT4 expression via NFKB and SREBP1 in skeletal muscle cells
Poletto A C, et al.
Molecular and Cellular Endocrinology, 401(12), 65-72 (2015)
A20 attenuates FFAs-induced lipid accumulation in nonalcoholic steatohepatitis
Ai L, et al.
International Journal of Biological Sciences, 11(12), 1436-1436 (2015)
Shuo Li et al.
International journal of biological sciences, 17(15), 4165-4175 (2021-11-23)
Background: Inflammation and apoptosis play a crucial role in the progression of nonalcoholic steatohepatitis (NASH). Suppressor of cytokine signaling 2 (SOCS2) is one of classic negative regulators of cytokine signaling, which has recently been described as anti-inflammatory mediators. However, the
Kangpeng Jin et al.
Theranostics, 10(12), 5290-5304 (2020-05-07)
Rationale: Inflammation plays a crucial role in the progression of nonalcoholic steatohepatitis (NASH). Protein tyrosine phosphatase receptor type O truncated isoform (PTPROt) is an integral membrane protein that has been identified in osteoclasts, macrophages, and B lymphocytes. However, its relationship
Pu Sun et al.
Journal for immunotherapy of cancer, 9(8) (2021-08-11)
The phosphatidylinositol 3-kinase (PI3K) is frequently hyperactivated in cancer and plays important roles in both malignant and immune cells. The effect of PI3Kα inhibitors on the tumor microenvironment (TME) remains largely unknown. Here, we investigated the modulation of the TME
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文章

Stearic Acid in Cell Culture

Supplement cell culture systems with fatty acids for biomanufacturing heterologous proteins like monoclonal antibodies.

細胞培養中的油酸

不飽和脂肪酸、油酸和其他細胞培養成分如何影響用於生物製造異源蛋白質（包括單克隆抗體）的無血清、無蛋白質細胞培養系統的性能。

Oleic Acid in Cell Culture

How the unsaturated fatty acid, oleic acid and other cell culture components affect the performance of serum-free, protein-free cell culture systems used for biomanufacturing heterologous proteins including monoclonal antibodies.

我們的科學家團隊在所有研究領域都有豐富的經驗，包括生命科學、材料科學、化學合成、色譜、分析等.

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