E1257

表皮生长因子 来源于鼠颔下腺

lyophilized powder, BioReagent, suitable for cell culture

• 同義詞: EGF, 表皮细胞生长因子
• CAS號碼: 62229-50-9
• EC號碼: 263-468-7
• MDL號碼: MFCD01634807
• 分類程式碼代碼: 12352202
• NACRES: NA.32

屬性

• 生物源: mouse submaxillary glands
• 品質等級: 200
• 產品線: BioReagent
• 化驗: ≥98% (SDS-PAGE)
• 形狀: lyophilized powder
• 效力: 0.02-2.0 ng/mL EC₅₀
• 包裝: pkg of 0.1 mg
• 儲存條件: avoid repeated freeze/thaw cycles
• 技術: cell culture | mammalian: suitable
• 雜質: endotoxin, tested
• 顏色: white
• UniProt登錄號: P01132
• 儲存溫度: 2-8°C
• 基因資訊: mouse ... Egf(13645)

描述

一般說明

Epidermal growth factor (EGF) is the member of EGF-like family of growth factors, that binds to EGF receptor.[1] It is majorly expressed in kidney,[2] parotid gland and salivary gland.[3]

應用

Epidermal Growth Factor from murine submaxillary gland has been used

• in studying its effects on the development of caustic esophageal stricture in rats[4]
• for preparation of MCF-10A cell line[5]
• for the culture of primary hair follicle stem cells from arbas cashmere goat (gHFSCs) and adhesion of hair follicles (HF)[6]

生化／生理作用

Epidermal growth factor (EGF) blocks gastric acid and pepsin secretion and increases gastrointestinal cell proliferation.[7] EGF stimulates proliferation and migration in bone marrow stromal cells (BMSC), that gives rise to osteoblasts, chondrocytes and adipocytes.[8] It functions as a strong mitogenic factor for various cultured cells. Mutations in this gene is linked to hypomagnesemia.[1] EGF plays a major role in the maintenance of hair and skin development.[9]

外觀

Lyophilized from 0.2 μm filtered solution in ammonium acetate buffer.

準備報告

Purified by gel filtration and ion-exchange chromatography.

分析報告

The biological activity is measured in a proliferation assay using BALB/MK cells.

安全資訊

• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: Eyeshields, Gloves, type N95 (US)