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重要文件

05292

Sigma-Aldrich

亚精胺0.1 M 溶液

Spermidine 0.1 M solution
1 of 1 reviewers received a sample product or took part in a promotion

同義詞:

亚精胺 溶液, 添加剂筛查溶液 30/试剂盒-No 78374

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About This Item

CAS號碼:
MDL號碼:
分類程式碼代碼:
12352200
PubChem物質ID:
NACRES:
NA.32
暫時無法取得訂價和供貨情況

品質等級

密度

1.00 g/mL at 20 °C

儲存溫度

2-8°C

SMILES 字串

NCCCCNCCCN

InChI

1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2

InChI 密鑰

ATHGHQPFGPMSJY-UHFFFAOYSA-N

基因資訊

mouse ... Odc1(18263)
rat ... Ppm1a(24666)

生化/生理作用

亚精胺是一种天然存在的多胺。它与多种细胞功能有关。它负责 DNA 在水溶液中的缩合和聚集。[1][2]已知亚精胺通过表观遗传修饰、诱导细胞死亡和抑制坏死来延长寿命。[3]
亚精胺0.1M溶液是添加剂筛选试剂盒的添加剂筛选液。添加剂筛选试剂盒设计用于快速方便地评价添加剂及其影响样品结晶的能力。添加剂试剂盒为精制结晶条件提供了工具。

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Eye Irrit. 2 - Skin Irrit. 2

儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Faceshields, Gloves, Goggles


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分析證明 (COA)

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存取文件庫

Induction of autophagy by spermidine promotes longevity.
Eisenberg T et al.
Nature Cell Biology, 11, 1305-1305 (2009)
Marjorie Catala et al.
Bio-protocol, 10(12), e3646-e3646 (2021-03-05)
Transfer RNAs (tRNAs) are heavily decorated with post-transcriptional modifications during their biosynthesis. To fulfil their functions within cells, tRNAs undergo a tightly controlled biogenesis process leading to the formation of mature tRNAs. In addition, functions of tRNAs are often modulated
53rd National Meeting of the Italian Society of Biochemistry and Molecular Biology (SIB) and National Meeting of Chemistry of Biological Systems ? Italian Chemical Society (SCI - Section CSB) (2008)
Satyanarayana U
Biochemistry (2014)
Lluís Millan-Ariño et al.
Current protocols in protein science, 102(1), e114-e114 (2020-10-01)
Histones are the major proteinaceous component of chromatin in eukaryotic cells and an important part of the epigenome, affecting most DNA-related events, including transcription, DNA replication, and chromosome segregation. The properties of histones are greatly influenced by their post-translational modifications

Questions

1–2 of 2 Questions  
  1. What is the pH of this spermidine solution please?

    1 answer
    1. The pH for this spermidine solution is not determined.

      Helpful?

  2. What is the solvent for this product? Is there an additive that allows it to remain stable at 4 degrees for an extended period of time?

    1 answer
    1. This product is a 0.1 M solution of spermidine in water. There is no preservative added. The material is sterile filtered and dispensed to autoclaved bottles. Thus microbial contamination is eliminated. Amines are oxidized by contact with air/oxygen. Stability will be maintained if the oxygen-free water is used for dilution and vial headspace is cleared of oxygen using an inert gas such as argon or nitrogen.

      Helpful?

Reviews

1 of 1 reviewers received a sample product or took part in a promotion

Active Filters

    • Review 1
    • Votes 0
    5 out of 5 stars.

    Dr.

    very good, my experiment got very good results_ thanks

    Helpful?

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