This product is supplied as a neat or pure liquid with a density of 0.925 g/mL and a molecular weight of 145.25 g/mol. The minimum purity is 99%, thus the molarity will vary slightly from lot to lot. The molarity can range from 6.3 M ( 99%) to 6.4 M (100%). The lot-specific purity is reported on the Certificate of Analysis.
推薦產品
生物源
synthetic
化驗
≥99% (GC)
形狀
solid or liquid (clear)
雜質
DNase, none detected
RNase, none detected
protease, none detected
折射率
n20/D 1.479 (lit.)
mp
22-25 °C
溶解度
water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow
密度
0.925 g/mL at 25 °C (lit.)
儲存溫度
room temp
SMILES 字串
NCCCCNCCCN
InChI
1S/C7H19N3/c8-4-1-2-6-10-7-3-5-9/h10H,1-9H2
InChI 密鑰
ATHGHQPFGPMSJY-UHFFFAOYSA-N
基因資訊
rat ... Ppm1a(24666)
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一般說明
一氧化氮合酶(nNOS)参与一氧化氮的生成。[1]
亚精胺是一种天然生物分子，以其广泛的健康益处而闻名，包括抗炎作用、抗氧化特性和呼吸功能改善作用。它在生理pH条件下带正电荷，因此能够与带相反电荷的DNA和RNA相互作用。饮食摄入亚精胺可降低神经退行性变、代谢疾病、心脏病和癌症风险。研究证明，亚精胺诱导的自噬可以通过清除大脑中的β淀粉样蛋白斑块来减缓认知能力下降的速度。补充亚精胺可改善线粒体代谢和翻译活性。此外，亚精胺对癌细胞表现出细胞自主作用，并影响它们与免疫效应子之间的通讯，导致肿瘤相关抗原识别和癌细胞死亡加速。亚精胺介导的自噬抑制癌细胞凋亡的激活，并与组织发育和细胞分化有关。这种天然化合物还因其神经保护和抗衰老特性而被认可，天然存在于精液和各种植物来源中。[2]
生化／生理作用
抑制神经元型一氧化氮合成酶（nNOS）。结合和沉淀DNA，可用于DNA结合蛋白纯化。激活T4聚核苷酸激酶活性。
抑制神经元型一氧化氮合成酶（nNOS）。结合和沉淀DNA；激活T4聚核苷酸激酶活性。
注意
如果需要无菌溶液，则应采用无菌过滤而非高压灭菌。时间一长，亚精胺将发生脱氨基作用；溶液应采用冷冻保存。通常需要配制新溶液。
其他說明
惰性气体中保存。空气敏感；强吸湿性。
訊號詞
Danger
危險聲明
危險分類
Eye Dam. 1 - Skin Corr. 1B
儲存類別代碼
8A - Combustible corrosive hazardous materials
水污染物質分類（WGK）
WGK 3
閃點（°F）
233.6 °F - closed cup
閃點（°C）
112 °C - closed cup
個人防護裝備
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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We have purchased S2626 spermidine 5 g. It does not say anywhere what molar concentration or if it is actually dissolved in water. Could you please inform me about that. I received 5 g i aprox 4 ml, and as I can read, the solubility is 50 mg /ml. ???
1 answer-
Helpful?
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Is the Molarity for all Spermidin batches the same ? Does the 6,4 M count also for xx-1G and xx-25G?
1 answer-
The molarity of this compound is the same for all pack sizes, but may vary slightly from lot to lot. The reported 6.4 M is assuming a 100% purity. The minimum purity specification is 99%.
Helpful?
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What is the molarity of Spermidine S2626-5G solution and what is the longterm storage condition?
1 answer-
This product is a neat or pure liquid. Based on a density of 0.925 g/mL and a molecular weight of 145.25, this material has an effective molarity of 6.4 M. It is recommended to store this solution as single-use aliquots at -20 ºC for no more than one month.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Helpful?
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Is this a spermidine solution or a neat liquid, and what is the concentration?
1 answer-
Based on a density of 0.925 g/mL and a molecular weight of 145.25, this neat liquid has an effective molarity of 6.4 M.
Helpful?
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