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Merck
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重要文件

4954

Sigma-Aldrich

Oleic Acid

同義詞:

Oleic Acid, cis-9-Octadecenoic Acid, 18:1

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About This Item

經驗公式（希爾表示法）:
C18H34O2
CAS號碼:
112-80-1
分子量：:
282.46
MDL號碼:
MFCD00064242
分類程式碼代碼:
12352211
NACRES:
NA.77
暫時無法取得訂價和供貨情況

化驗

≥99% (GC)

品質等級

100

形狀

liquid

製造商／商標名

Calbiochem®

儲存條件

OK to freeze

顏色

colorless

溶解度

chloroform: 10 mg/mL
ethanol: 5 mg/mL

密度

0.89 g/mL

運輸包裝

ambient

儲存溫度

2-8°C

SMILES 字串

OC(=O)CCCCCCC\C=C\CCCCCCCC

InChI

1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9+

InChI 密鑰

ZQPPMHVWECSIRJ-MDZDMXLPSA-N

一般說明

A cis-unsaturated fatty acid that has been shown to activate protein kinase C in hepatocytes. Potentiates acetylcholine receptor currents by activating CaM kinase II, independent of the PKC pathway.
Unsaturated fatty acid that has been shown to activate protein kinase C in hepatocytes. Density: 0.89 g/ml.

生化／生理作用

Cell permeable: no
Product does not compete with ATP.
Reversible: no

包裝

Packaged under inert gas

警告

Toxicity: Standard Handling (A)

其他說明

Nishizaki, T., et al. 1997. NeuroReport 8, 597.
Bessesen, D.H., et al. 1993. J. Lipid Res.34, 229.
Felden, F., et al. 1993. Biochem. Biophys. Res. Commun.190, 602.
Williams, L.L., et al. 1993. Proc. Soc. Exp. Biol. Med.202, 239.
Diaz-Guerra, M.J. 1991. J. Biol. Chem.266, 23568.

法律資訊

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

儲存類別代碼

10 - Combustible liquids

水污染物質分類（WGK）

WGK 1

分析證明 (COA)

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M J Díaz-Guerra et al.
The Journal of biological chemistry, 266(35), 23568-23576 (1991-12-15)
The effect of oleate on the subcellular distribution of protein kinase C (PKC) was studied in isolated hepatocytes and in perfused rat liver in the presence of physiological concentrations of serum albumin. A time- and dose-dependent translocation of PKC from
T Nishizaki et al.
Neuroreport, 8(3), 597-601 (1997-02-10)
Oleic acid, a cis-unsaturated free fatty acid, is proposed to be involved in the protein kinase C (PKC) activation pathway. Its biological actions, however, have not been well-characterized. We examined the effects of oleic acid on acetylcholine (ACh)-gated channel currents
F Felden et al.
Biochemical and biophysical research communications, 190(2), 602-608 (1993-01-29)
The free fatty acid (FFA) concentration in the epididymal cytosol of the adult rat was found to be 20-fold higher than in the serum. The binding of [3H] dihydrotestosterone to epididymal rat androgen binding protein (rABP) was modified by physiological
L L Williams et al.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 202(2), 239-245 (1993-02-01)
The polyunsaturated omega-6 fatty acid, arachidonic acid ([AA] 20:4n-6), is both the key of the immunoregulatory substances, prostaglandins, and leukotrienes, and an essential component of immune cell membrane phospholipids, providing stability and flexibility to ensure cellular function. To explore possible
D H Bessesen et al.
Journal of lipid research, 34(2), 229-238 (1993-02-01)
Lipoprotein lipase (LPL) is important for the delivery of triglyceride fatty acids (TGFA) to a variety of tissues. We have used measurements of heparin-releasable LPL activity, immunohistochemistry, in situ hybridization, and Northern analysis to more fully characterize the location of

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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