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48599

2,3,7,8-Tetrachlorodibenzo-p-dioxin solution

analytical standard

Synonim(y):

2,3,7,8-TCDD

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Informacje o tej pozycji

Numer CAS:
UNSPSC Code:
12352200
EC Number:
203-625-9


grade

analytical standard

CofA

current certificate can be downloaded

packaging

ampule of 1 mL

storage temp.

2-8°C

InChI

1S/C12H4Cl4O2/c13-5-1-9-10(2-6(5)14)18-12-4-8(16)7(15)3-11(12)17-9/h1-4H

InChI key

HGUFODBRKLSHSI-UHFFFAOYSA-N

General description

2,3,7,8-Tetrachlorodibenzo-p-dioxin is the most potent congener of dioxins and dioxin-like chemicals, which can exert adverse effects in laboratory animals used in testing.
2,3,7,8-Tetrachlorodibenzo-p-dioxin is a highly distributed environmental contaminant[1], released by industrial activities, which can act like as a reproductive toxicant and endocrine disruptor in all vertebrates.[2]

Application

2,3,7,8-Tetrachlorodibenzo-p-dioxin solution has been used as standard in investigating the effect of 2,3,7,8-Tetrachlorodibenzo-p-dioxin to offsprings of fish, using high performance gas chromatography coupled with high performance mass spectrometry (HPGC-HPMS).[2]
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
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signalword

Danger

Hazard Classifications

Aquatic Chronic 1 - Asp. Tox. 1 - Flam. Liq. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

target_organs

Central nervous system

Klasa składowania

3 - Flammable liquids

wgk

WGK 3

flash_point_f

39.2 °F - closed cup

flash_point_c

4 °C - closed cup


Wykazy regulacyjne

Wykazy regulacyjne dotyczą głównie produktów chemicznych. Można w nich podawać ograniczoną liczbę informacji na temat produktów niechemicznych. Brak wpisu oznacza, że żaden ze składników nie znajduje się w wykazie. Użytkownik odpowiada za zagwarantowanie bezpiecznego i zgodnego z prawem stosowania produktu.

108-88-3

CAS No.


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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów



Hongtao Shang et al.
Environment international, 54, 50-58 (2013-02-19)
A total of 60 paired samples of earthworm, corresponding soil and wormcast were collected to investigate the bioaccumulation tendency of polychlorinated dibenzo-p-dioxins/dibenzofurans (PCDD/Fs), polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) in earthworms from a typical E-waste dismantling area in
E C Rada et al.
Chemosphere, 110, 53-61 (2014-06-02)
Atmospheric depositions of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and polychlorinated biphenyls (PCBs) were monitored at three sites in the vicinity of a steel making plant, located in an Italian alpine valley. A high variability in the deposition of PCDD/Fs was
K A Solak et al.
Toxicology, 311(3), 124-134 (2013-07-23)
The aryl hydrocarbon receptor (AhR) is involved in a wide variety of biological and toxicological responses, including neuroendocrine signaling. Due to the complexity of neuroendocrine pathways in e.g. the hypothalamus and pituitary, there are limited in vitro models available despite



Numer pozycji handlu globalnego

SKUNUMER GTIN
4859904061838086556

Questions

1–4 of 4 Questions  
  1. Can I get pure 2,3,7,8-Tetrachlorodibenzo-p-dioxin from Sigma-Aldrich?

    1 answer
    1. No; Sigma-Aldrich has no source for pure 2,3,7,8-Tetrachlorodibenzo-p-dioxin.  It is only available as Supelco 48599: 2,3,7,8-TCDD, 10 μg/mL in toluene, ampule of 1mL.

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  2. What is the molecular weight of 2,3,7,8-Tetrachlorodibenzo-p-dioxin, Product 48599?

    1 answer
    1. The molecular weight of 2,3,7,8-TCDD is 321.97 Da.

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  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  4. Is Product No. 48599, 2,3,7,8-Tetrachlorodibenzo-p-dioxin solution, appropriate for use in tissue culture studies?

    1 answer
    1. The 2,3,7,8-Tetrachlorodibenzo-p-dioxin solution (10 μg/mL in toluene), is sold as 1mL in a flame sealed ampule.  It is made to be used as a chemical standard with US EPA drinking and wastewater analytical methods.  We have no knowledge of its use in tissue culture.

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