SML1489
FICZ
≥95% (HPLC), lyophilized powder, AhR agonist
Synonim(y):
5,11-Dihydro-indolo[3,2-b]carbazole-6-carboxaldehyde, 6-Formylindolo[3,2-b]carbazole
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About This Item
Wzór empiryczny (zapis Hilla):
C19H12N2O
Numer CAS:
Masa cząsteczkowa:
284.31
Kod UNSPSC:
12352200
NACRES:
NA.77
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product name
FICZ, ≥95% (HPLC)
Poziom jakości
Próba
≥95% (HPLC)
Postać
lyophilized powder
kolor
yellow
rozpuszczalność
DMSO: 0.5 mg/mL, clear (warmed)
temp. przechowywania
−20°C
Działania biochem./fizjol.
FICZ (6-formylindolo(3,2b)carbazole) being a photooxidation product of tryptophan, might serve as a chemical messenger of light.
FICZ is a potent high affinity ligand of the aryl hydrocarbon receptor (AhR), which is a ligand-activated transcription factor that activates the expression of aromatic hydrocarbon metabolizing enzyme genes such as the CYP1A1 gene and has also been shown to have multiple additional roles in cell-cycle regulation, development and maturation of many tissues, control of inflammation, and immune response. FICZ is a photoproduct of tryptophan and is believed to be an endogenous AhR ligand. It is extremely potent, with a Kd value of 0.07 nM.
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Hasło ostrzegawcze
Warning
Zwroty wskazujące rodzaj zagrożenia
Zwroty wskazujące środki ostrożności
Klasyfikacja zagrożeń
Acute Tox. 4 Oral
Kod klasy składowania
11 - Combustible Solids
Klasa zagrożenia wodnego (WGK)
WGK 1
Temperatura zapłonu (°F)
Not applicable
Temperatura zapłonu (°C)
Not applicable
Certyfikaty analizy (CoA)
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