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S3523

Sigma-Aldrich

Surfactin

from Bacillus subtilis, ≥98.0% (HPLC)

Synonim(y):

surfaktyna C

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10 MG
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10 MG
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50 MG
7970,00 zł

About This Item

Wzór empiryczny (zapis Hilla):
C53H93N7O13
Numer CAS:
24730-31-2
Masa cząsteczkowa:
1036.34
Kod UNSPSC:
51102829
Identyfikator substancji w PubChem:
24899562
NACRES:
NA.85

2030,00 zł

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pochodzenie biologiczne

Bacillus subtilis

Poziom jakości

200

opis

zwitterionic

Próba

≥98.0% (HPLC)

Formularz

powder

warunki przechowywania

(Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)

kolor

white to faint yellow

CMC

7.5-20 μmol/L (depending on methods)

rozpuszczalność

ethanol: soluble 10 mg/mL

spektrum działania antybiotyku

Gram-negative bacteria
Gram-positive bacteria
fungi
mycoplasma
neoplastics
viruses

Tryb działania

cell membrane | interferes

temp. przechowywania

2-8°C

ciąg SMILES

CC(C)CCCCCCCCC[C@@H]1CC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)O1

InChI

1S/C53H93N7O13/c1-30(2)20-18-16-14-13-15-17-19-21-36-28-43(61)54-37(22-23-44(62)63)47(66)55-38(24-31(3)4)48(67)57-40(26-33(7)8)51(70)60-46(35(11)12)52(71)58-41(29-45(64)65)50(69)56-39(25-32(5)6)49(68)59-42(27-34(9)10)53(72)73-36/h30-42,46H,13-29H2,1-12H3,(H,54,61)(H,55,66)(H,56,69)(H,57,67)(H,58,71)(H,59,68)(H,60,70)(H,62,63)(H,64,65)/t36-,37+,38+,39-,40-,41+,42+,46+/m1/s1

Klucz InChI

NJGWOFRZMQRKHT-WGVNQGGSSA-N

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Opis ogólny

Chemical structure: peptide

Zastosowanie

Surfactin is used as a surfactant to mediate flux of mono-and divalent cations, such as calcium, across lipid bilayer membranes. It is also used to study antitumor activity, activity against enveloped viruses, activity against the protoplast of Bacillus megaterium and the activity against Mycoplasma[1].

Działania biochem./fizjol.

Surfactin is a lipopeptide antibiotic that is composed of one β-hydroxy fatty acid, which has a long fatty acid moiety, and seven amino acids. Three of them have D configurations. It is a powerful biosurfactant that causes lysis of erythrocytes and bacteria. It is also a clotting inhibitor. Surfactin is thought to disrupt or disintegrate membranes via physicochemical interaction with the membranes[1].

Inne uwagi

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
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Kod klasy składowania

11 - Combustible Solids

Klasa zagrożenia wodnego (WGK)

WGK 3

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable

Środki ochrony indywidualnej

Eyeshields, Gloves, type N95 (US)

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Certyfikaty analizy (CoA)

Lot/Batch Number
0000422734
0000422734
0000411103
0000411103
0000369072

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

M M Nakano et al.
Journal of bacteriology, 170(12), 5662-5668 (1988-12-01)
Surfactin is a lipopeptide antibiotic produced by the cells of Bacillus subtilis ATCC 21332. A genetic locus responsible for surfactin production (sfp) was transferred from ATCC 21332 to JH642, a derivative of the standard B. subtilis 168. To study the
Darlane Wellen Freitas de Oliveira et al.
Colloids and surfaces. B, Biointerfaces, 101, 34-43 (2012-07-17)
In this work a low cost medium for the production of a biosurfactant by Bacillus subtilis LAMI005 and the kinetics of surfactin production considering the effect of initial substrate concentration were investigated. First, cashew apple juice supplementation for optimal production
Guillaume Henry et al.
Cellular microbiology, 13(11), 1824-1837 (2011-08-16)
The lipopeptide surfactin secreted by plant-beneficial bacilli has crucial biological functions among which the ability to stimulate immune-related responses in host tissues. This phenomenon is important for biological control of plant diseases but its molecular basis is still poorly understood.
N Behary et al.
Colloids and surfaces. B, Biointerfaces, 90, 137-143 (2011-11-08)
This article deals with an alternative method for bio-separation of surfactin produced by Bacillus subtilis using sorption method on nonwoven PET (polyethylene terephthalate) fibrous membranes functionalized with chitosan. In the first part of the study, surface functionalization of the PET
Junfeng Zhao et al.
Journal of industrial microbiology & biotechnology, 39(6), 889-896 (2012-02-22)
Genome shuffling is an efficient approach for the rapid improvement of the yield of secondary metabolites. This study was undertaken to enhance the yield of surfactin produced by Bacillus amyloliquefaciens ES-2-4 using genome shuffling and to examine changes in SrfA
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  1. How can I determine the shelf life / expiration / retest date of this product?

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    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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