L135

L-741,626

≥98% (HPLC)

• Synonim(y): (±)-3-[4-(4-Chlorophenyl)-4-hydroxypiperidinyl]methylindole
• Wzór empiryczny (zapis Hilla): C₂₀H₂₁ClN₂O
• Numer CAS: 81226-60-0
• Masa cząsteczkowa: 340.85
• NACRES: NA.77
• PubChem Substance ID: 24278529
• UNSPSC Code: 12352200
• MDL number: MFCD00953632
• Assay: ≥98% (HPLC)
• Form: powder

Właściwości

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: ≥20 mg/mL, ethanol: 24 mg/mL, H₂O: insoluble
• storage temp.: room temp
• SMILES string: OC1(CCN(CC1)Cc2c[nH]c3ccccc23)c4ccc(Cl)cc4
• InChI: 1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2
• InChI key: LLBLNMUONVVVPG-UHFFFAOYSA-N
• Gene Information: human ... DRD2(1813), DRD3(1814), DRD4(1815)

Opis

Application

L-741,626 has been used as selective dopamine (D₂) receptor antagonist to study its effects on the uptake of dopamine in human embryonic kidney 293 (HEK293) cells. It has also been used as a D₂ receptor antagonist to study its effects on thyrotropin-releasing hormone (TRH) induced prolactin release.

Biochem/physiol Actions

L-741,626 is a selective dopamine (D₂) receptor antagonist.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Informacja o środkach bezpieczeństwa

• Klasa składowania: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)